Synucleinopathies are a group of neurodegenerative diseases with common pathological
lesions associated with the excessive accumulation and abnormal intracellular deposition of …

For a long time, studies of amyloidogenic proteins and peptides (amyloidogenic PPs) have
been focused basically on their harmful properties and association with diseases. A vast …

Alzheimer's disease (AD) is characterized by several neuropathological changes, mainly
extracellular amyloid aggregates (plaques), intraneuronal inclusions of phosphorylated tau …

Circular RNAs (circRNAs) are single-stranded RNA molecules often circularized by
backsplicing. Growing evidence implicates circRNAs in the underlying mechanisms of …

Analyzing the therapeutic potential of a therapeutic biomolecule requires an understanding
of how it may interact with proteins and modify their corresponding functions. α-Synuclein is …

Synucleinopathies are a set of devastating neurodegenerative diseases that share a
pathologic accumulation of the protein α-synuclein (α-syn). This accumulation causes …

Dream-enactment behavior that emerges during episodes of rapid eye movement (REM)
sleep without muscle atonia is a parasomnia known as REM sleep behavior disorder (RBD) …

Simple Summary Emerging evidence on synucleins and astrocytes warrants closer
inspection of their functional relationship. The expression and release of synucleins from the …

Intrinsically disordered proteins (IDPs), which can interact with many partner proteins, are
central to many physiological functions and to various pathologies that include …

Abstract α-Synucleinopathies are a group of neurodegenerative disorders characterized by
alterations in α-synuclein (α-syn), a protein associated with membrane phospholipids …