The airway epithelium, which lines the conducting airways, is central to the defense of the
lungs against inhaled particulate matter and pathogens such as SARS-CoV-2, the virus that …

The essential and redundant functions of human type I and II interferons (IFNs) have been
delineated over the last three decades by studies of patients with inborn errors of immunity …

Rationale: Pharmacological improvement of CFTR function with elexacaftor/tezacaftor/
ivacaftor (ETI) provides unprecedented improvements in lung function and other clinical …

Lung-resident and circulatory lymphoid, myeloid, and stromal cells, expressing various
pattern recognition receptors (PRRs), detect pathogen-and danger-associated molecular …

Background The intensified search for low-threshold herbal anti-viral drugs would be of
great advantage in prevention of early stages of infection. Since the SARS-CoV-2 Omicron …

Objectives To investigate effects of ETI on the transcriptome of nasal epithelial and immune
cells from children with CF at the single-cell level. Methods Nasal swabs from 13 children …

Since the creation of the glucose enzyme sensor in the early 1960s by Clark and Lyons [1],
biosensors have entered a new era in the detection and tracking of biologically relevant …