IL6 modulates the immune status of the tumor microenvironment to facilitate metastatic colonization of colorectal cancer cells

Y Toyoshima, H Kitamura, H Xiang, Y Ohno… - Cancer Immunology …, 2019 - AACR
It is unknown as to how liver metastases are correlated with host immune status in colorectal
cancer. In this study, we found that IL6, a proinflammatory cytokine produced in tumor …

Cytoreductive surgery and HIPEC for peritoneal metastases combined with curative treatment of colorectal liver metastases: systematic review of all literature and …

EMV De Cuba, R Kwakman, DL Knol, HJ Bonjer… - Cancer treatment …, 2013 - Elsevier
OBJECTIVE: Assess the overall outcome in colorectal cancer (CRC) patients that present
with a combination of peritoneal metastases (PM) and liver metastases (CRLM) after …

Eradication of unresectable liver metastasis through induction of tumour specific energy depletion

D Huo, J Zhu, G Chen, Q Chen, C Zhang, X Luo… - Nature …, 2019 - nature.com
Abstract Treatment of liver metastasis experiences slow progress owing to the severe side
effects. In this study, we demonstrate a strategy capable of eliminating metastatic cancer …

Cytoreductive surgery and intraperitoneal chemotherapy for colorectal peritoneal carcinomatosis: prognosis and treatment of recurrences in a cohort study

PH Cashin, W Graf, P Nygren, H Mahteme - European Journal of Surgical …, 2012 - Elsevier
BACKGROUND: Cytoreductive surgery (CRS) and intraperitoneal chemotherapy (IPC)
treatment of colorectal peritoneal carcinomatosis (PC) is gaining acceptance, but …

[HTML][HTML] Intensified follow-up in colorectal cancer patients using frequent Carcino-Embryonic Antigen (CEA) measurements and CEA-triggered imaging: Results of the …

CJ Verberne, Z Zhan, E Van Den Heuvel… - European Journal of …, 2015 - Elsevier
Aim The value of frequent Carcino-Embryonic Antigen (CEA) measurements and CEA-
triggered imaging for detecting recurrent disease in colorectal cancer (CRC) patients was …

Should patients with peritoneal carcinomatosis of colorectal origin with synchronous liver metastases be treated with a curative intent? A case-control study

L Maggiori, D Goéré, B Viana, D Tzanis… - Annals of …, 2013 - journals.lww.com
Objective: This study aimed to assess the prognostic impact of liver metastases (LM) in
patients with colorectal peritoneal carcinomatosis (PC) who underwent complete …

Prediction of mortality in metastatic colorectal cancer in a real-life population: a multicenter explorative analysis

H Rumpold, D Niedersüß-Beke, C Heiler, D Falch… - BMC cancer, 2020 - Springer
Background Metastatic colorectal cancer (mCRC) remains a lethal disease. Survival,
however, is increasing due to a growing number of treatment options. Yet due to the number …

Oligometastasis: past, present, future

SI Gutiontov, SP Pitroda, RR Weichselbaum - International Journal of …, 2020 - Elsevier
In this review, we discuss the oligometastatic state, with a focus on its current and future
relevance within the field of radiation therapy. We first outline the scope of the problem and …

Colon cancer

AB Benson, JP Arnoletti, T Bekaii-Saab, E Chan… - Journal of the National …, 2011 - jnccn.org
Colorectal cancer is the fourth most frequently diagnosed cancer and the second leading
cause of cancer death in the United States. In 2011, an estimated 101,340 new cases of …

Liver transplantation for colorectal liver metastases: revisiting the concept

A Foss, R Adam, S Dueland - Transplant international, 2010 - Wiley Online Library
Liver transplantation (Lt) for colorectal cancer (CRC) liver metastases is no more considered
due to the poor outcome observed up to the 1990s. According to the European Liver …