Synaptic abnormalities are a cardinal feature of Alzheimer's disease (AD) that are known to
arise as the disease progresses. A growing body of evidence suggests that pathological …

Geroscience, the new interdisciplinary field that aims to understand the relationship between
aging and chronic age-related diseases (ARDs) and geriatric syndromes (GSs), is based on …

Background The results from cross sectional and longitudinal studies show that periodontitis
is closely associated with cognitive impairment (CI) and Alzhemer's Disease (AD). Further …

Background: Inflammation is a part of the first line of defense of the body against invasive
pathogens, and plays a crucial role in tissue regeneration and repair. A proper inflammatory …

Classically, the CNS is described as displaying immune privilege, as it shows attenuated
responses to challenge by alloantigen. However, the CNS does show local inflammation in …

Ischaemia–reperfusion (I–R) injury, initiated via bursts of reactive oxygen species produced
during the reoxygenation phase following hypoxia, is well known in a variety of acute …

Oral diseases, such as caries and periodontitis, not only have local effects on the dentition
and on tooth‐supporting tissues but also may impact a number of systemic conditions …

The aim of this study was to establish a link between periodontal disease and Alzheimer's
disease (AD) with a view to identifying the major periodontal disease bacteria (Treponema …

Alzheimer's disease (AD) is a neurodegenerative disorder that causes cognitive decline,
memory loss, and inability to perform everyday functions. Hallmark features of AD …

Alzheimer's disease (AD) is the most frequent type of dementia. The pathological hallmarks
of the disease are extracellular senile plaques composed of beta-amyloid peptide (Aβ) and …