[HTML][HTML] Efficacy of acetylcholinesterase inhibitors in Alzheimer's disease
G Marucci, M Buccioni, D Dal Ben, C Lambertucci… - …, 2021 - Elsevier
Abstract Alzheimer's disease (AD), the most common cause of adult-onset dementia is
characterized by a progressive decline of cognitive functions accompanied by behavioral …
characterized by a progressive decline of cognitive functions accompanied by behavioral …
The Keap1–Nrf2–ARE pathway as a potential preventive and therapeutic target: an update
MC Lu, JA Ji, ZY Jiang, QD You - Medicinal research reviews, 2016 - Wiley Online Library
Abstract The Keap1–Nrf2–ARE ((Kelch‐like ECH‐Associating protein 1) nuclear factor
erythroid 2 related factor 2‐antioxidant response element) pathway is one of the most …
erythroid 2 related factor 2‐antioxidant response element) pathway is one of the most …
Nrf2–ARE pathway: an emerging target against oxidative stress and neuroinflammation in neurodegenerative diseases
Neurodegenerative diseases (NDDs) are predicted to be the biggest health concern in this
century and the second leading cause of death by 2050. The main risk factor of these …
century and the second leading cause of death by 2050. The main risk factor of these …
NRF2 as a therapeutic target in neurodegenerative diseases
MS Brandes, NE Gray - ASN neuro, 2020 - journals.sagepub.com
Increased reactive oxygen species production and oxidative stress have been implicated in
the pathogenesis of numerous neurodegenerative conditions including among others …
the pathogenesis of numerous neurodegenerative conditions including among others …
NRF2 and cancer: the good, the bad and the importance of context
MB Sporn, KT Liby - Nature Reviews Cancer, 2012 - nature.com
Many studies of chemopreventive drugs have suggested that their beneficial effects on
suppression of carcinogenesis and many other chronic diseases are mediated through …
suppression of carcinogenesis and many other chronic diseases are mediated through …
Small molecule modulators of K eap1‐N rf2‐ARE pathway as potential preventive and therapeutic agents
S Magesh, Y Chen, L Hu - Medicinal research reviews, 2012 - Wiley Online Library
K elch‐like ECH‐associated protein 1 (K eap1)‐nuclear factor erythroid 2‐related factor 2 (N
rf2)‐antioxidant response elements (ARE) pathway represents one of the most important …
rf2)‐antioxidant response elements (ARE) pathway represents one of the most important …
Emerging roles of Nrf2 and phase II antioxidant enzymes in neuroprotection
Phase II metabolic enzymes are a battery of critical proteins that detoxify xenobiotics by
increasing their hydrophilicity and enhancing their disposal. These enzymes have long been …
increasing their hydrophilicity and enhancing their disposal. These enzymes have long been …
The adverse effects of air pollution on the nervous system
Exposure to ambient air pollution is a serious and common public health concern associated
with growing morbidity and mortality worldwide. In the last decades, the adverse effects of air …
with growing morbidity and mortality worldwide. In the last decades, the adverse effects of air …
Neuroprotection against oxidative stress: Phytochemicals targeting TrkB signaling and the Nrf2-ARE antioxidant system
Oxidative stress (OS) plays a critical role in the pathophysiology of several brain-related
disorders, including neurodegenerative diseases and ischemic stroke, which are the major …
disorders, including neurodegenerative diseases and ischemic stroke, which are the major …
Contribution of the Nrf2 pathway on oxidative damage and mitochondrial failure in Parkinson and Alzheimer's disease
F Villavicencio Tejo, RA Quintanilla - Antioxidants, 2021 - mdpi.com
The increase in human life expectancy has become a challenge to reduce the deleterious
consequences of aging. Nowadays, an increasing number of the population suffer from age …
consequences of aging. Nowadays, an increasing number of the population suffer from age …