Abstract Alzheimer's disease (AD), the most common cause of adult-onset dementia is
characterized by a progressive decline of cognitive functions accompanied by behavioral …

Abstract The Keap1–Nrf2–ARE ((Kelch‐like ECH‐Associating protein 1) nuclear factor
erythroid 2 related factor 2‐antioxidant response element) pathway is one of the most …

Neurodegenerative diseases (NDDs) are predicted to be the biggest health concern in this
century and the second leading cause of death by 2050. The main risk factor of these …

Increased reactive oxygen species production and oxidative stress have been implicated in
the pathogenesis of numerous neurodegenerative conditions including among others …

Many studies of chemopreventive drugs have suggested that their beneficial effects on
suppression of carcinogenesis and many other chronic diseases are mediated through …

K elch‐like ECH‐associated protein 1 (K eap1)‐nuclear factor erythroid 2‐related factor 2 (N
rf2)‐antioxidant response elements (ARE) pathway represents one of the most important …

Phase II metabolic enzymes are a battery of critical proteins that detoxify xenobiotics by
increasing their hydrophilicity and enhancing their disposal. These enzymes have long been …

Exposure to ambient air pollution is a serious and common public health concern associated
with growing morbidity and mortality worldwide. In the last decades, the adverse effects of air …

Oxidative stress (OS) plays a critical role in the pathophysiology of several brain-related
disorders, including neurodegenerative diseases and ischemic stroke, which are the major …

The increase in human life expectancy has become a challenge to reduce the deleterious
consequences of aging. Nowadays, an increasing number of the population suffer from age …