Iron is an essential trace element for most organisms. A common way for bacteria to acquire
this nutrient is through the secretion of siderophores, which are secondary metabolites that …

Assembly-line polyketide synthases (PKSs) are among the most complex protein
machineries known in nature, responsible for the biosynthesis of numerous compounds …

Microorganisms produce a wealth of structurally diverse specialized metabolites with a
remarkable range of biological activities and a wide variety of applications in medicine and …

Although biosynthetic gene clusters (BGCs) have been discovered for hundreds of bacterial
metabolites, our knowledge of their diversity remains limited. Here, we used a novel …

Planctomycetes are ubiquitous, environmentally and biotechnologically important bacteria
that are key players in global carbon and nitrogen cycles. Ever since their first discovery in …

Members of the 'Bacillus subtilis group'include some of the most commercially important
bacteria, used for the production of a wide range of industrial enzymes and fine …

Lipopeptides constitute a structurally diverse group of metabolites produced by various
bacterial and fungal genera. In the past decades, research on lipopeptides has been fueled …

Soil-and plant-associated environments harbor numerous bacteria that produce antibiotic
metabolites with specific or broad-spectrum activities against coexisting microorganisms …

Nonribosomal peptides and polyketides are a diverse group of natural products with
complex chemical structures and enormous pharmaceutical potential. They are synthesized …

Actinomycetes are historically important sources for secondary metabolites (SMs) with
applications in human medicine, animal health, and plant crop protection. It is now clear that …