Engineered biomaterials for in situ tissue regeneration

AK Gaharwar, I Singh, A Khademhosseini - Nature Reviews Materials, 2020 - nature.com
In situ tissue regeneration harnesses the body's regenerative potential to control cell
functions for tissue repair. The design of biomaterials for in situ tissue engineering requires …

Nanoparticle surface functionalization: how to improve biocompatibility and cellular internalization

G Sanità, B Carrese, A Lamberti - Frontiers in molecular biosciences, 2020 - frontiersin.org
The use of nanoparticles (NP) in diagnosis and treatment of many human diseases,
including cancer, is of increasing interest. However, cytotoxic effects of NPs on cells and the …

Engineering immunomodulatory and osteoinductive implant surfaces via mussel adhesion-mediated ion coordination and molecular clicking

T Wang, J Bai, M Lu, C Huang, D Geng, G Chen… - Nature …, 2022 - nature.com
Immune response and new tissue formation are important aspects of tissue repair. However,
only a single aspect is generally considered in previous biomedical interventions, and the …

[HTML][HTML] Toxicity of manufactured nanomaterials

Y Liu, S Zhu, Z Gu, C Chen, Y Zhao - Particuology, 2022 - Elsevier
Manufactured nanomaterials with unique properties have been extensively applied in
various industrial, agricultural or medical fields. However, some of the properties have been …

Zinc silicate/nano-hydroxyapatite/collagen scaffolds promote angiogenesis and bone regeneration via the p38 MAPK pathway in activated monocytes

Y Song, H Wu, Y Gao, J Li, K Lin, B Liu… - … Applied Materials & …, 2020 - ACS Publications
Recent studies show that biomaterials are capable of regulating immune responses to
induce a favorable osteogenic microenvironment and promote osteogenesis and …

Nanostructured Titanium Implant Surface Facilitating Osseointegration from Protein Adsorption to Osteogenesis: The Example of TiO2 NTAs

B Wu, Y Tang, K Wang, X Zhou… - International journal of …, 2022 - Taylor & Francis
Titanium implants have been widely applied in dentistry and orthopedics due to their
biocompatibility and resistance to mechanical fatigue. TiO2 nanotube arrays (TiO2 NTAs) on …

Immunomodulatory biomaterials and their application in therapies for chronic inflammation-related diseases

JR Nakkala, Z Li, W Ahmad, K Wang, C Gao - Acta Biomaterialia, 2021 - Elsevier
The degree of tissue injuries such as the level of scarring or organ dysfunction, and the
immune response against them primarily determine the outcome and speed of healing …

Silk sericin as building blocks of bioactive materials for advanced therapeutics

D Hu, T Li, Y Wang, M Feng, J Sun - Journal of Controlled Release, 2023 - Elsevier
Silk sericin is a class of protein biopolymers produced by silkworms. Increasing attention has
been paid to silk sericin for biomedical applications in the last decade, not only because of …

Artificial engineering of the protein corona at bio-nano interfaces for improved cancer-targeted nanotherapy

S Khan, M Sharifi, JP Gleghorn, MMN Babadaei… - Journal of Controlled …, 2022 - Elsevier
Nanoparticles (NPs) have been used in numerous applications as anticancer, antibacterial
and antioxidant agents. Artificial engineering of protein interactions with NPs in biological …

Reactive oxygen species–degradable polythioketal urethane foam dressings to promote porcine skin wound repair

P Patil, KA Russo, JT McCune, AC Pollins… - Science translational …, 2022 - science.org
Porous, resorbable biomaterials can serve as temporary scaffolds that support cell
infiltration, tissue formation, and remodeling of nonhealing skin wounds. Synthetic …