Atopic dermatitis is a common inflammatory skin disease with a strong heritable component.
Pathogenetic models consider keratinocyte differentiation defects and immune alterations as …

Background Atopic dermatitis (AD) is a common skin disease characterized by recurrent
episodes of itching. Genetic variation associated with the persistence of AD has not been …

Atopic dermatitis (AD) is a complex multifactorial inflammatory skin disease that affects~ 280
million people worldwide. About 85% of AD cases begin in childhood, a significant portion of …

Background Atopic dermatitis (AD) is an inflammatory skin condition that can occur in early
life, predisposing to asthma development in a phenomenon known as the atopic march …

The Netherlands Twin Register (NTR) began in 1987 with data collection in twins and their
families, including families with newborn twins and triplets. Twenty-five years later, the NTR …

Background Atopic dermatitis (AD) is the most common allergic disease in the world. While
genetic components play critical roles in its pathophysiology, a large proportion of its genetic …

This review focuses on genome-wide association studies (GWASs) of asthma and allergic
diseases published between January 1, 2018, and June 30, 2019. During this time period …

Background Atopic dermatitis (AD) is a major inflammatory condition of the skin caused by
inherited skin barrier deficiency, with mutations in the filaggrin gene predisposing to …

Atopic dermatitis and psoriasis are the two most common immune-mediated inflammatory
disorders affecting the skin. Genome-wide studies demonstrate a high degree of genetic …

Multiple sclerosis (MS) is an autoimmune disorder where T cells attack neurons in the
central nervous system (CNS) leading to demyelination and neurological deficits. A driver of …