Global differences in atopic dermatitis

NHA Suaini, CPT Tan, EXL Loo… - Pediatric Allergy and …, 2021 - Wiley Online Library
Atopic dermatitis (AD) is a chronic inflammatory skin disorder, with a highly variable
prevalence worldwide. Recent evidence, however, has shown an increase in prevalence in …

JAK inhibition and progressive kidney disease

FC Brosius III, JC He - Current opinion in nephrology and …, 2015 - journals.lww.com
JAK inhibition and progressive kidney disease : Current Opinion in Nephrology and Hypertension
JAK inhibition and progressive kidney disease : Current Opinion in Nephrology and …

A distal enhancer at risk locus 11q13.5 promotes suppression of colitis by Treg cells

R Nasrallah, CJ Imianowski, L Bossini-Castillo… - Nature, 2020 - nature.com
Genetic variations underlying susceptibility to complex autoimmune and allergic diseases
are concentrated within noncoding regulatory elements termed enhancers. The functions of …

A mouse model for atopic dermatitis using topical application of vitamin D3 or of its analog MC903

V Moosbrugger-Martinz, M Schmuth… - Inflammation: Methods and …, 2017 - Springer
Atopic dermatitis (AD) is a chronic relapsing inflammatory skin disease with pruritus and
high prevalence. Indeed, 15–30% of children and 2–10% of adults from industrialized …

Pharmacodynamics of Janus kinase inhibitors for the treatment of atopic dermatitis

L Calabrese, A Chiricozzi, C De Simone… - Expert Opinion on …, 2022 - Taylor & Francis
Introduction Atopic dermatitis (AD) is the most common inflammatory skin disorder. Despite
the high disease burden, the therapeutic options are limited and their efficacy in controlling …

Genetic, clinical, and environmental factors associated with persistent atopic dermatitis in childhood

S Thorsteinsdottir, J Stokholm, JP Thyssen… - JAMA …, 2019 - jamanetwork.com
Importance Knowledge about factors associated with persistence of atopic dermatitis (AD)
during childhood is sparse. Objective To explore heritable, environmental, and clinical …

Genetics of allergic diseases

RA Ortiz, KC Barnes - Immunology and Allergy Clinics, 2015 - immunology.theclinics.com
Coca and Cooke were the first to describe asthma, atopic dermatitis (AD), allergic rhinitis
(AR), food allergy, and urticaria as “phenomena of hypersensitiveness” at the annual …

Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris

AA Navarini, MA Simpson, M Weale, J Knight… - Nature …, 2014 - nature.com
Acne vulgaris (acne) is a common inflammatory disorder of the cutaneous pilo-sebaceous
unit. Here we perform a genome-wide association analysis in the United Kingdom …

The multi-modal immune pathogenesis of atopic eczema

K Eyerich, S Eyerich, T Biedermann - Trends in immunology, 2015 - cell.com
Atopic eczema (AE) is one of the most common inflammatory diseases, often constituting a
lifelong burden for afflicted individuals. Recent findings have provided new insights into the …

Regulatory Mechanism of the IL-33–IL-37 Axis via Aryl Hydrocarbon Receptor in Atopic Dermatitis and Psoriasis

G Tsuji, K Yamamura, K Kawamura… - International journal of …, 2023 - mdpi.com
Interleukin (IL)-33 and IL-37 have been identified as novel cytokines involved in various
inflammatory diseases. However, their specific roles remain largely unknown. Recent …