Progressing nanotechnology to improve targeted cancer treatment: overcoming hurdles in its clinical implementation
M Chehelgerdi, M Chehelgerdi, OQB Allela… - Molecular cancer, 2023 - Springer
The use of nanotechnology has the potential to revolutionize the detection and treatment of
cancer. Developments in protein engineering and materials science have led to the …
cancer. Developments in protein engineering and materials science have led to the …
Multidrug resistance in cancer: understanding molecular mechanisms, immunoprevention and therapeutic approaches
Cancer is one of the leading causes of death worldwide. Several treatments are available for
cancer treatment, but many treatment methods are ineffective against multidrug-resistant …
cancer treatment, but many treatment methods are ineffective against multidrug-resistant …
Recent progress in bioconjugation strategies for liposome-mediated drug delivery
In nanoparticle (NP)-mediated drug delivery, liposomes are the most widely used drug
carrier, and the only NP system currently approved by the FDA for clinical use, owing to their …
carrier, and the only NP system currently approved by the FDA for clinical use, owing to their …
Aptamer-functionalized nanoparticles in targeted delivery and cancer therapy
Z Fu, J Xiang - International Journal of Molecular Sciences, 2020 - mdpi.com
Using nanoparticles to carry and delivery anticancer drugs holds much promise in cancer
therapy, but nanoparticles per se are lacking specificity. Active targeting, that is, using …
therapy, but nanoparticles per se are lacking specificity. Active targeting, that is, using …
Investigations on the interface of nucleic acid aptamers and binding targets
S Cai, J Yan, H Xiong, Y Liu, D Peng, Z Liu - Analyst, 2018 - pubs.rsc.org
Nucleic acid aptamers are single-stranded DNA or RNA of 20–100 nucleotides in length that
have attracted substantial scientific interest due to their ability to specifically bind to target …
have attracted substantial scientific interest due to their ability to specifically bind to target …
[HTML][HTML] Biomedical applications of aptamer-modified chitosan nanomaterials: An updated review
S Fathi-Karkan, S Mirinejad, F Ulucan-Karnak… - International Journal of …, 2023 - Elsevier
Among polysaccharides of environmental and economic interest, chitosan (CS) is receiving
much attention, particularly in the food and biotechnology industries to encapsulate active …
much attention, particularly in the food and biotechnology industries to encapsulate active …
Recent development of aptamer conjugated chitosan nanoparticles as cancer therapeutics
A Sheikh, S Md, NA Alhakamy, P Kesharwani - International Journal of …, 2022 - Elsevier
There is a surge in demand for safe and targeted therapy against cancer as the conventional
treatment approach fails to reach the specific site. Chemotherapeutic agents are generally …
treatment approach fails to reach the specific site. Chemotherapeutic agents are generally …
Aptamer-functionalized liposomes for targeted cancer therapy
SA Moosavian, P Kesharwani, V Singh… - … Nanocarriers for Cancer …, 2023 - Elsevier
Liposomes are among the most well-documented drug delivery systems in anticancer
therapy owing to their passive targeting capacities besides inherent biocompatibility and …
therapy owing to their passive targeting capacities besides inherent biocompatibility and …
Nanomedicine combats drug resistance in lung cancer
Lung cancer is the second most prevalent cancer and the leading cause of cancer‐related
death worldwide. Surgery, chemotherapy, molecular targeted therapy, immunotherapy, and …
death worldwide. Surgery, chemotherapy, molecular targeted therapy, immunotherapy, and …
Aptamers as versatile ligands for biomedical and pharmaceutical applications
B Guan, X Zhang - International journal of nanomedicine, 2020 - Taylor & Francis
Aptamers are a class of targeting ligands that bind exclusively to biomarkers of interest.
Aptamers have been identified as candidates for the construction of various smart systems …
Aptamers have been identified as candidates for the construction of various smart systems …