Progressing nanotechnology to improve targeted cancer treatment: overcoming hurdles in its clinical implementation

M Chehelgerdi, M Chehelgerdi, OQB Allela… - Molecular cancer, 2023 - Springer
The use of nanotechnology has the potential to revolutionize the detection and treatment of
cancer. Developments in protein engineering and materials science have led to the …

Multidrug resistance in cancer: understanding molecular mechanisms, immunoprevention and therapeutic approaches

TB Emran, A Shahriar, AR Mahmud, T Rahman… - Frontiers in …, 2022 - frontiersin.org
Cancer is one of the leading causes of death worldwide. Several treatments are available for
cancer treatment, but many treatment methods are ineffective against multidrug-resistant …

Recent progress in bioconjugation strategies for liposome-mediated drug delivery

B Almeida, OK Nag, KE Rogers, JB Delehanty - Molecules, 2020 - mdpi.com
In nanoparticle (NP)-mediated drug delivery, liposomes are the most widely used drug
carrier, and the only NP system currently approved by the FDA for clinical use, owing to their …

Aptamer-functionalized nanoparticles in targeted delivery and cancer therapy

Z Fu, J Xiang - International Journal of Molecular Sciences, 2020 - mdpi.com
Using nanoparticles to carry and delivery anticancer drugs holds much promise in cancer
therapy, but nanoparticles per se are lacking specificity. Active targeting, that is, using …

Investigations on the interface of nucleic acid aptamers and binding targets

S Cai, J Yan, H Xiong, Y Liu, D Peng, Z Liu - Analyst, 2018 - pubs.rsc.org
Nucleic acid aptamers are single-stranded DNA or RNA of 20–100 nucleotides in length that
have attracted substantial scientific interest due to their ability to specifically bind to target …

[HTML][HTML] Biomedical applications of aptamer-modified chitosan nanomaterials: An updated review

S Fathi-Karkan, S Mirinejad, F Ulucan-Karnak… - International Journal of …, 2023 - Elsevier
Among polysaccharides of environmental and economic interest, chitosan (CS) is receiving
much attention, particularly in the food and biotechnology industries to encapsulate active …

Recent development of aptamer conjugated chitosan nanoparticles as cancer therapeutics

A Sheikh, S Md, NA Alhakamy, P Kesharwani - International Journal of …, 2022 - Elsevier
There is a surge in demand for safe and targeted therapy against cancer as the conventional
treatment approach fails to reach the specific site. Chemotherapeutic agents are generally …

Aptamer-functionalized liposomes for targeted cancer therapy

SA Moosavian, P Kesharwani, V Singh… - … Nanocarriers for Cancer …, 2023 - Elsevier
Liposomes are among the most well-documented drug delivery systems in anticancer
therapy owing to their passive targeting capacities besides inherent biocompatibility and …

Nanomedicine combats drug resistance in lung cancer

X Zheng, X Song, G Zhu, D Pan, H Li, J Hu… - Advanced …, 2024 - Wiley Online Library
Lung cancer is the second most prevalent cancer and the leading cause of cancer‐related
death worldwide. Surgery, chemotherapy, molecular targeted therapy, immunotherapy, and …

Aptamers as versatile ligands for biomedical and pharmaceutical applications

B Guan, X Zhang - International journal of nanomedicine, 2020 - Taylor & Francis
Aptamers are a class of targeting ligands that bind exclusively to biomarkers of interest.
Aptamers have been identified as candidates for the construction of various smart systems …