Microneedle‐assisted transdermal delivery of nanoparticles: Recent insights and prospects

AJ Guillot, M Martínez‐Navarrete… - Wiley …, 2023 - Wiley Online Library
Transdermal delivery of drugs offers an interesting alternative for the administration of
molecules that present certain troubles when delivered by the oral route. It can produce …

Polymeric microneedles: an emerging paradigm for advanced biomedical applications

D Kulkarni, D Gadade, N Chapaitkar, S Shelke… - Scientia …, 2023 - mdpi.com
Microneedles are gaining popularity as a new paradigm in the area of transdermal drug
delivery for biomedical and healthcare applications. Efficient drug delivery with minimal …

Development of hydrogel-forming microneedles for transdermal delivery of albendazole from liquid reservoir

AYR Aziz, NA Hasir, NBP Imran… - Journal of …, 2023 - Taylor & Francis
Albendazole (ABZ) is an anthelmintic agent from the benzimidazole group, known as the
broad-spectrum antiparasitic drug. ABZ is commonly used to treat human intestinal and …

Flexible Topical Hydrogel Patch Loaded with Antimicrobial Drug for Accelerated Wound Healing

S Saeed, K Barkat, MU Ashraf, M Shabbir, I Anjum… - Gels, 2023 - mdpi.com
A hydrogel topical patch of neomycin was developed by using sodium alginate (SA) and
hydroxyethylcellulose (HEC) as polymers. Free radical polymerization in an aqueous …

Dissolving and Swelling Hydrogel-Based Microneedles: An Overview of Their Materials, Fabrication, Characterization Methods, and Challenges

B Shriky, M Babenko, BR Whiteside - Gels, 2023 - mdpi.com
Polymeric hydrogels are a complex class of materials with one common feature—the ability
to form three-dimensional networks capable of imbibing large amounts of water or biological …

Preclinical evaluation of a microparticle-based transdermal vaccine patch against metastatic breast cancer

RU Zaman, RP Gala, A Bansal, P Bagwe… - International Journal of …, 2022 - Elsevier
Breast cancer is the number one cause of cancer-related deaths among females. Current
chemotherapy targets both tumor and normal cells, leading to pronounced side effects …

Dissolving microneedle patches for delivery of amniotic mesenchymal stem cell metabolite products for skin regeneration in UV-aging induced mice

A Miatmoko, BS Hariawan, DM Cahyani… - European Journal of …, 2024 - Elsevier
Microneedles offer a promising solution to enhancing dermal delivery of amniotic
mesenchymal stem cell metabolite product (AMSC-MP), which contains hydrophilic protein …

Trilayer dissolving microneedle for transdermal delivery of minoxidil: a proof-of-concept study

N Afika, AF Saniy, AA Fawwaz Dharma… - Journal of …, 2024 - Taylor & Francis
Alopecia areata (AA) is a chronic autoimmune disease characterized by bald patches in
certain areas of the body, especially the scalp. Minoxidil (MNX), as a first-line treatment of …

Assessment of formulation variables of poor water soluble diacerein for its improved loading and anti-inflammatory activity

M Shabbir, K Barkat, MU Ashraf, U Nagra… - Drug Delivery and …, 2023 - Springer
Dissolving microneedles have become a popular method for percutaneous administrationof
drugs. However, loading poorly soluble drugs into water-based dissolving microneedles …

[HTML][HTML] Machine Learning Assists in the Design and Application of Microneedles

W He, S Kong, R Lin, Y Xie, S Zheng, Z Yin, X Huang… - Biomimetics, 2024 - mdpi.com
Microneedles (MNs), characterized by their micron-sized sharp tips, can painlessly
penetrate the skin and have shown significant potential in disease treatment and …