Small cell lung cancer (SCLC) is characterized by rapid growth and high metastatic capacity.
It has strong epidemiologic and biologic links to tobacco carcinogens. Although the majority …

Small cell lung cancer (SCLC) is a rapidly growing, highly metastatic, and relatively immune-
cold lung cancer subtype. Historically viewed in the laboratory and clinic as a single …

Radiation therapy is a mainstay of cancer treatment but does not always lead to complete
tumor regression. Here we combine radiotherapy with blockade of the 'don't-eat-me'cell …

We performed comprehensive proteogenomic characterization of small cell lung cancer
(SCLC) using paired tumors and adjacent lung tissues from 112 treatment-naive patients …

Brain metastases represent an important clinical problem for patients with small-cell lung
cancer (SCLC). However, the mechanisms underlying SCLC growth in the brain remain …

Small cell lung cancer (SCLC) is a recalcitrant neuroendocrine carcinoma with dismal
survival outcomes. A major barrier in the field has been the relative paucity of human tumors …

Background Fibronectin, an extracellular matrix protein, has been reported to be associated
with heterogeneous cancer stemness, angiogenesis and progression in multiple cancer …

The present review aimed to establish an understanding of the pathophysiology of
leptomeningeal disease as it relates to late-stage development among different cancer …

Small cell lung cancer (SCLC) is an extremely aggressive neuroendocrine tumor,
accounting for approximated 13% of all lung cancer cases. SCLC is characterized by rapid …

Neuroendocrine neoplasms (NENs) can develop in almost any organ and span a spectrum
from well-differentiated and indolent neuroendocrine tumours (NETs) to poorly differentiated …