The recent emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
and the ensuing global pandemic has presented a health emergency of unprecedented …

The COVID‐19 pandemic has become an urgent issue in every country. Based on recent
reports, the most severely ill patients present with coagulopathy, and disseminated …

Tissue factor (TF) is the high-affinity receptor and cofactor for factor (F) VII/VIIa. The TF-FVIIa
complex is the primary initiator of blood coagulation and plays an essential role in …

Viral infections are dangerous diseases for human health worldwide, which lead to
significant morbidity and mortality each year. Because of their importance and the lack of …

Without an approved vaccine or treatments, Ebola outbreak management has been limited
to palliative care and barrier methods to prevent transmission. These approaches, however …

For almost 50 years, ebolaviruses and related filoviruses have been repeatedly reemerging
across the vast equatorial belt of the African continent to cause epidemics of highly fatal …

Platelets are anucleate blood cells that play a crucial role in the maintenance of hemostasis.
While platelet activation and elevated platelet counts (thrombocytosis) are associated with …

Outbreaks of Ebola hemorrhagic fever in sub-Saharan Africa are associated with case
fatality rates of up to 90%. Currently, neither a vaccine nor an effective antiviral treatment is …

Ebola viruses are the causative agents of a severe form of viral haemorrhagic fever in man,
designated Ebola haemorrhagic fever, and are endemic in regions of central Africa. The …

Despite extensive global efforts in the fight against killer infectious diseases, they still cause
one in four deaths worldwide and are important causes of long-term functional disability …