Vitamin D: Sources, physiological role, biokinetics, deficiency, therapeutic use, toxicity, and overview of analytical methods for detection of vitamin D and its …

J Janoušek, V Pilařová, K Macáková… - Critical reviews in …, 2022 - Taylor & Francis
Vitamin D has a well-known role in the calcium homeostasis associated with the
maintenance of healthy bones. It increases the efficiency of the intestinal absorption of …

[HTML][HTML] Vitamin D metabolism, mechanism of action, and clinical applications

DD Bikle - Chemistry & biology, 2014 - cell.com
Vitamin D 3 is made in the skin from 7-dehydrocholesterol under the influence of UV light.
Vitamin D 2 (ergocalciferol) is derived from the plant sterol ergosterol. Vitamin D is …

[HTML][HTML] Assessment of vitamin D status–a changing landscape

M Herrmann, CJL Farrell, I Pusceddu… - Clinical Chemistry and …, 2017 - degruyter.com
In recent years it has been shown that vitamin D deficiency is associated with an increased
incidence as well as the progression of a broad range of diseases including osteoporosis …

A narrative role of vitamin D and its receptor: with current evidence on the gastric tissues

S Sirajudeen, I Shah, A Al Menhali - International journal of molecular …, 2019 - mdpi.com
Vitamin D is a major steroid hormone that is gaining attention as a therapeutic molecule.
Due to the general awareness of its importance for the overall well-being, vitamin D …

Epimers of vitamin D: a review

B Al-Zohily, A Al-Menhali, S Gariballa, A Haq… - International journal of …, 2020 - mdpi.com
In this review, we discuss the sources, formation, metabolism, function, biological activity,
and potency of C3-epimers (epimers of vitamin D). We also determine the role of epimerase …

Recommendations on the measurement and the clinical use of vitamin D metabolites and vitamin D binding protein–A position paper from the IFCC Committee on …

K Makris, HP Bhattoa, E Cavalier, K Phinney… - Clinica Chimica …, 2021 - Elsevier
Vitamin D, an important hormone with a central role in calcium and phosphate homeostasis,
is required for bone and muscle development as well as preservation of musculoskeletal …

The vitamin D metabolome: An update on analysis and function

C Jenkinson - Cell biochemistry and function, 2019 - Wiley Online Library
Current understanding of vitamin D tends to be focussed on the measurement of the major
circulating form 25‐hydroxyvitamin D3 (25OHD3) and its conversion to the active hormonal …

[HTML][HTML] Vitamin D status is associated with uteroplacental dysfunction indicated by pre-eclampsia and small-for-gestational-age birth in a large prospective pregnancy …

ME Kiely, JY Zhang, M Kinsella, AS Khashan… - The American journal of …, 2016 - Elsevier
Background: Associations between vitamin D and pregnancy outcomes have been
inconsistent. Objectives: We described the distribution of 25-hydroxyvitamin D3 [25 (OH) …

The association between circulating 25-hydroxyvitamin D metabolites and type 2 diabetes in European populations: a meta-analysis and Mendelian randomisation …

JS Zheng, J Luan, E Sofianopoulou, SJ Sharp… - PLoS …, 2020 - journals.plos.org
Background Prior research suggested a differential association of 25-hydroxyvitamin D (25
(OH) D) metabolites with type 2 diabetes (T2D), with total 25 (OH) D and 25 (OH) D3 …

Vitamin D testing: advantages and limits of the current assays

B Altieri, E Cavalier, HP Bhattoa… - European journal of …, 2020 - nature.com
Vitamin D deficiency and insufficiency has become a pandemic health problem with a
consequent increase of requests for determining circulating levels of 25-hydroxyvitamin D …