Evolving concepts of the vulnerable atherosclerotic plaque and the vulnerable patient: implications for patient care and future research

P Gaba, BJ Gersh, J Muller, J Narula… - Nature Reviews …, 2023 - nature.com
Understanding the natural history of coronary artery atherosclerosis is necessary to
determine prognosis and prescribe effective therapies. Traditional management of coronary …

Coronary Computed Tomographic Angiography for Complete Assessment of Coronary Artery Disease: JACC State-of-the-Art Review

PW Serruys, H Hara, S Garg, H Kawashima… - Journal of the American …, 2021 - jacc.org
Coronary computed tomography angiography (CTA) has shown great technological
improvements over the last 2 decades. High accuracy of CTA in detecting significant …

Clinical quantitative coronary artery stenosis and coronary atherosclerosis imaging: a Consensus Statement from the Quantitative Cardiovascular Imaging Study …

AJV Mézquita, F Biavati, V Falk, H Alkadhi… - Nature Reviews …, 2023 - nature.com
The detection and characterization of coronary artery stenosis and atherosclerosis using
imaging tools are key for clinical decision-making in patients with known or suspected …

Coronary atherosclerotic plaque activity and future coronary events

A Moss, M Daghem, E Tzolos, MN Meah… - JAMA …, 2023 - jamanetwork.com
Importance Recurrent coronary events in patients with recent myocardial infarction remain a
major clinical problem. Noninvasive measures of coronary atherosclerotic disease activity …

Machine learning with 18F-sodium fluoride PET and quantitative plaque analysis on CT angiography for the future risk of myocardial infarction

J Kwiecinski, E Tzolos, MN Meah, S Cadet… - Journal of Nuclear …, 2022 - Soc Nuclear Med
Coronary 18F-sodium fluoride (18F-NaF) PET and CT angiography–based quantitative
plaque analysis have shown promise in refining risk stratification in patients with coronary …

Native aortic valve disease progression and bioprosthetic valve degeneration in patients with transcatheter aortic valve implantation

J Kwiecinski, E Tzolos, TRG Cartlidge, A Fletcher… - Circulation, 2021 - Am Heart Assoc
Background: Major uncertainties remain regarding disease activity within the retained native
aortic valve, and regarding bioprosthetic valve durability, after transcatheter aortic valve …

Noninvasive plaque imaging to accelerate coronary artery disease drug development

GA Figtree, PD Adamson, C Antoniades… - Circulation, 2022 - Am Heart Assoc
Coronary artery disease (CAD) remains the leading cause of adult mortality globally.
Targeting known modifiable risk factors has had substantial benefit, but there remains a …

[HTML][HTML] Computed tomographic angiography in coronary artery disease

PW Serruys, N Kotoku, BL Nørgaard, S Garg… - …, 2023 - ncbi.nlm.nih.gov
Coronary computed tomographic angiography (CCTA) is becoming the first-line
investigation for establishing the presence of coronary artery disease and, with fractional …

Coronary 18F-Fluoride Uptake and Progression of Coronary Artery Calcification

MK Doris, MN Meah, AJ Moss… - Circulation …, 2020 - Am Heart Assoc
Background Positron emission tomography (PET) using 18F-sodium fluoride (18F-fluoride)
to detect microcalcification may provide insight into disease activity in coronary …

Thoracic Aortic 18F-Sodium Fluoride Activity and Ischemic Stroke in Patients With Established Cardiovascular Disease

AJ Fletcher, YY Tew, E Tzolos, SS Joshi… - Cardiovascular …, 2022 - jacc.org
Background Aortic atherosclerosis represents an important contributor to ischemic stroke
risk. Identifying patients with high-risk aortic atheroma could improve preventative treatment …