[HTML][HTML] Mitochondrial management of reactive oxygen species
Mitochondria in aerobic eukaryotic cells are both the site of energy production and the
formation of harmful species, such as radicals and other reactive oxygen species, known as …
formation of harmful species, such as radicals and other reactive oxygen species, known as …
[HTML][HTML] Patient care standards for primary mitochondrial disease: a consensus statement from the Mitochondrial Medicine Society
The purpose of this statement is to provide consensus-based recommendations for optimal
management and care for patients with primary mitochondrial disease. This statement is …
management and care for patients with primary mitochondrial disease. This statement is …
[HTML][HTML] Treatable inborn errors of metabolism causing intellectual disability: a systematic literature review
CDM van Karnebeek, S Stockler - Molecular genetics and metabolism, 2012 - Elsevier
BACKGROUND: Intellectual disability ('developmental delay'at age< 5years) affects 2.5% of
population worldwide. Recommendations to investigate genetic causes of intellectual …
population worldwide. Recommendations to investigate genetic causes of intellectual …
Mechanisms of mitochondrial diseases
E Ylikallio, A Suomalainen - Annals of medicine, 2012 - Taylor & Francis
Mitochondria are essential organelles with multiple functions, the most well known being the
production of adenosine triphosphate (ATP) through oxidative phosphorylation (OXPHOS) …
production of adenosine triphosphate (ATP) through oxidative phosphorylation (OXPHOS) …
[HTML][HTML] Metabolic regulation to treat bipolar depression: mechanisms and targeting by trimetazidine
S Khanra, P Reddy, A Giménez-Palomo… - Molecular …, 2023 - nature.com
Bipolar disorder's core feature is the pathological disturbances in mood, often accompanied
by disrupted thinking and behavior. Its complex and heterogeneous etiology implies that a …
by disrupted thinking and behavior. Its complex and heterogeneous etiology implies that a …
Primary and secondary coenzyme Q10 deficiency: the role of therapeutic supplementation
M Potgieter, E Pretorius, MS Pepper - Nutrition reviews, 2013 - academic.oup.com
Abstract Coenzyme Q10 (CoQ10) is the only lipid-soluble antioxidant that animal cells
synthesize de novo. It is found in cell membranes and is particularly well known for its role in …
synthesize de novo. It is found in cell membranes and is particularly well known for its role in …
Mitochondrial protein functions elucidated by multi-omic mass spectrometry profiling
JA Stefely, NW Kwiecien, EC Freiberger… - Nature …, 2016 - nature.com
Mitochondrial dysfunction is associated with many human diseases, including cancer and
neurodegeneration, that are often linked to proteins and pathways that are not well …
neurodegeneration, that are often linked to proteins and pathways that are not well …
Mitochondrial COQ9 is a lipid-binding protein that associates with COQ7 to enable coenzyme Q biosynthesis
DC Lohman, F Forouhar, ET Beebe… - Proceedings of the …, 2014 - National Acad Sciences
Coenzyme Q (CoQ) is an isoprenylated quinone that is essential for cellular respiration and
is synthesized in mitochondria by the combined action of at least nine proteins (COQ1–9) …
is synthesized in mitochondria by the combined action of at least nine proteins (COQ1–9) …
[PDF][PDF] Cerebellar ataxia and coenzyme Q deficiency through loss of unorthodox kinase activity
JA Stefely, F Licitra, L Laredj, AG Reidenbach… - Molecular cell, 2016 - cell.com
The UbiB protein kinase-like (PKL) family is widespread, comprising one-quarter of
microbial PKLs and five human homologs, yet its biochemical activities remain obscure …
microbial PKLs and five human homologs, yet its biochemical activities remain obscure …
Droplet size and composition of nutraceutical nanoemulsions influences bioavailability of long chain fatty acids and Coenzyme Q10
HT Cho, L Salvia-Trujillo, J Kim, Y Park, H Xiao… - Food Chemistry, 2014 - Elsevier
The influence of droplet size (d 32= 0.21, 0.70 or 2.2 μm) and oil digestibility (corn oil versus
mineral oil) on the bioavailability of a model long chain fatty acid (heptadecanoic acid) and …
mineral oil) on the bioavailability of a model long chain fatty acid (heptadecanoic acid) and …