Mitochondria in aerobic eukaryotic cells are both the site of energy production and the
formation of harmful species, such as radicals and other reactive oxygen species, known as …

The purpose of this statement is to provide consensus-based recommendations for optimal
management and care for patients with primary mitochondrial disease. This statement is …

BACKGROUND: Intellectual disability ('developmental delay'at age< 5years) affects 2.5% of
population worldwide. Recommendations to investigate genetic causes of intellectual …

Mitochondria are essential organelles with multiple functions, the most well known being the
production of adenosine triphosphate (ATP) through oxidative phosphorylation (OXPHOS) …

Bipolar disorder's core feature is the pathological disturbances in mood, often accompanied
by disrupted thinking and behavior. Its complex and heterogeneous etiology implies that a …

Abstract Coenzyme Q10 (CoQ10) is the only lipid-soluble antioxidant that animal cells
synthesize de novo. It is found in cell membranes and is particularly well known for its role in …

Mitochondrial dysfunction is associated with many human diseases, including cancer and
neurodegeneration, that are often linked to proteins and pathways that are not well …

Coenzyme Q (CoQ) is an isoprenylated quinone that is essential for cellular respiration and
is synthesized in mitochondria by the combined action of at least nine proteins (COQ1–9) …

The UbiB protein kinase-like (PKL) family is widespread, comprising one-quarter of
microbial PKLs and five human homologs, yet its biochemical activities remain obscure …

The influence of droplet size (d 32= 0.21, 0.70 or 2.2 μm) and oil digestibility (corn oil versus
mineral oil) on the bioavailability of a model long chain fatty acid (heptadecanoic acid) and …