Racial differences in cancer susceptibility and survival: more than the color of the skin?

BC Özdemir, GP Dotto - Trends in cancer, 2017 - cell.com
Epidemiological studies point to race as a determining factor in cancer susceptibility. In US
registries recording cancer incidence and survival by race (distinguishing 'black versus …

EGFR-mutated oncogene-addicted non-small cell lung cancer: current trends and future prospects

JC Soria, TS Mok, F Cappuzzo, PA Jänne - Cancer treatment reviews, 2012 - Elsevier
Non-small cell lung cancer (NSCLC) tumours with certain mutations in the epidermal growth
factor receptor (EGFR) tyrosine kinase have been termed 'oncogene addicted'to reflect their …

Development and in vitro evaluation of core–shell type lipid–polymer hybrid nanoparticles for the delivery of erlotinib in non-small cell lung cancer

B Mandal, NK Mittal, P Balabathula, LA Thoma… - European journal of …, 2016 - Elsevier
Core–shell type lipid–polymer hybrid nanoparticles (CSLPHNPs) have emerged as a
multifunctional drug delivery platform. The delivery system combines mechanical …

[HTML][HTML] Overexpression of MAGE-A9 is predictive of poor prognosis in epithelial ovarian cancer

Y Xu, C Wang, Y Zhang, L Jia, J Huang - Scientific reports, 2015 - nature.com
The cancer testis antigen, melanoma-associated antigen A9 (MAGE-A9), is expressed in
many kinds of different human cancers and is an important target for immunotherapy …

[HTML][HTML] High expression of MAGE-A9 in tumor and stromal cells of non-small cell lung cancer was correlated with patient poor survival

S Zhang, X Zhai, G Wang, J Feng, H Zhu… - … journal of clinical and …, 2015 - ncbi.nlm.nih.gov
Melanoma associated antigen-A (MAGE-A) is an oncogene and correlated with tumor
initiation and development. However the roles of MAGE-A9 in non-small cell lung cancer …

Dual stimuli-responsive release of aptamer AS1411 decorated erlotinib loaded chitosan nanoparticles for non-small-cell lung carcinoma therapy

K Saravanakumar, A Sathiyaseelan… - Carbohydrate …, 2020 - Elsevier
The present work was developed the pH dependent-aptamer AS1411 (APT) decorated and
erlotinib (En) loaded chitosan nanoparticles (CSNPs) for promising non-small-cell lung …

The function of RAS mutation in cancer and advances in its drug research

S Chen, F Li, D Xu, K Hou, W Fang… - Current pharmaceutical …, 2019 - ingentaconnect.com
RAS (H-ras, K-ras, and N-ras), as the second largest mutated gene driver in various human
cancers, has long been a vital research target for cancer. Its function is to transform the …

Omics and drug response

UA Meyer, UM Zanger, M Schwab - Annual review of …, 2013 - annualreviews.org
A new generation of technologies commonly named omics permits assessment of the
entirety of the components of biological systems and produces an explosion of data and a …

Brachyury, a driver of the epithelial–mesenchymal transition, is overexpressed in human lung tumors: an opportunity for novel interventions against lung cancer

M Roselli, RI Fernando, F Guadagni, A Spila… - Clinical Cancer …, 2012 - AACR
Purpose: The epithelial–mesenchymal transition (EMT) is emerging as a critical factor for the
progression and metastasis of carcinomas, as well as drug resistance. The T-box …

Targeted therapies for lung cancer: clinical experience and novel agents

JE Larsen, T Cascone, DE Gerber… - The Cancer …, 2011 - journals.lww.com
Although lung cancer remains the leading cancer killer in the United States, recently a
number of developments indicate future clinical benefit. These include evidence that …