Systemic autoimmune diseases (SAIDs), such as systemic lupus erythematosus (SLE),
systemic sclerosis (SSc) and rheumatoid arthritis (RA), are fully related to the unregulated …

Background: Alzheimer's disease (AD) is a neurodegenerative disease that remains
uncured. Its pathogenesis is characterized by the formation of β-amyloid (Aβ) plaques. The …

Despite major progress in the treatment of autoimmune diseases in the past two decades,
most therapies do not cure disease and can be associated with increased risk of infection …

Chimeric antigen receptor (CAR) T‐cell therapy is a form of immunotherapy where the
lymphocytes, mostly T‐cells, are redirected to specifically recognize and eliminate a target …

The conventional clinical therapies for autoimmune diseases (ADs) lack specificity,
necessitating long-term medication that can lead to serious side effects. In contrast, chimeric …

Recent advances in gene and cell therapy showed impressive results over last decade that
culminated into approval of CAR-T therapies, ie, long-term remissions in hopeless cancer …

Biotechnology has revolutionized the fields of rheumatology and immunology, providing
innovative solutions for understanding and treating autoimmune diseases. Traditionally …

Just a few weeks ago at the American Society of Hematology Annual Meeting, Mueller et al.
presented remarkable data from their ongoing study testing CD19-directed chimeric antigen …