Abstract α-Synuclein (α-Syn) is closely related to the pathogenesis of Parkinson's disease
(PD). Under pathological conditions, the conformation of α-syn changes and different forms …

Dopaminergic neurons are constantly threatened by the thin boundaries between functional
α-synuclein (AS) structural disorder and pathogenic aggregation, and between dopamine …

Parkinson's disease (PD) pathology is characterized by the loss of dopaminergic neurons of
the nigrostriatal system and accumulation of Lewy bodies (LB) and Lewy neurites (LN) …

Objective The objective of this study was to investigate the outcomes of microneurosurgical
interventions on V1 segment of the vertebral artery in patients with refractory vertebrobasilar …

Oxidation–reduction post-translational modifications (redox-PTMs) are chemical alterations
to amino acids of proteins. Redox-PTMs participate in the regulation of protein conformation …

Abstract MicroRNA-29a (miR-29a) has been suggested to serve a potential protective
function against Parkinson's disease (PD); however, the exact molecular mechanisms …

The small neuronal protein α-synuclein (αS) is found in pre-synaptic terminals and plays a
role in vesicle recycling and neurotransmission. Fibrillar aggregates of αS are the hallmark …

It is well‐known that people suffering from hyperglycemia have a higher propensity to
develop Parkinson's disease (PD). One of the most plausible mechanisms linking these two …

Phosphorylation of α-synuclein protein at serine-129 (Ser129P) is a widely used marker for
disease pathology in neurodegenerative disorders termed synucleinopathies. In …