Abstract Calcium (Ca 2+) signaling is critical for cell function and cell survival. Mitochondria
play a major role in regulating the intracellular Ca 2+ concentration ([Ca 2+] i). Mitochondrial …

Calcium ion (Ca2+) plays a critical role in the cardiac mitochondria function. Ca2+ entering
the mitochondria is necessary for ATP production and the contractile activity of …

The invasion of Candida albicans is one of the most common fungal infections seen in
clinical practice, and serious drug resistance has been reported in recent years. Therefore …

Mitochondrial Ca2+ homeostasis regulates energy production, cell division, and cell death.
The basic properties of mitochondrial Ca2+ uptake have been firmly established. The Ca2+ …

Background Myocardial infarction (MI) is associated with high mortality rates, despite the fact
that there are therapies available. Importantly, excessive oxidative stress may contribute to …

Abstract N-(3-oxododecanoyl)-l-homoserine lactone is a Pseudomonas aeruginosa
secreted quorum-sensing molecule that mediates the secretion of virulence factors, biofilm …

Recent studies have revealed that a small amount of cisplatin can penetrate into the nucleus
and induce intranuclear DNA damage. Specifically, most cisplatin accumulates in and …

Cardiac arrhythmias are among the most important pathologies that lead to sudden death.
The discovery of new therapeutic options against arrhythmias with low adverse effects is of …

Objectives: To evaluate the role of FOXO3 during the process of mitophagy induced by
manganese chloride (MnCl2), mitochondrial dysfunction and mitophagy were detected …

Calcium (Ca2+) transport by mitochondria is an important component of the cell Ca2+
homeostasis machinery in metazoans. Ca2+ uptake by mitochondria is a major determinant …