Regulation of GFAP expression

M Brenner, A Messing - ASN neuro, 2021 - journals.sagepub.com
Expression of the GFAP gene has attracted considerable attention because its onset is a
marker for astrocyte development, its upregulation is a marker for reactive gliosis, and its …

Association of donanemab treatment with exploratory plasma biomarkers in early symptomatic Alzheimer disease: a secondary analysis of the TRAILBLAZER-ALZ …

MJ Pontecorvo, M Lu, SC Burnham, AE Schade… - JAMA …, 2022 - jamanetwork.com
Importance Plasma biomarkers of Alzheimer disease may be useful as minimally invasive
pharmacodynamic measures of treatment outcomes. Objective To analyze the association of …

Plasma glial fibrillary acidic protein is elevated in cognitively normal older adults at risk of Alzheimer's disease

P Chatterjee, S Pedrini, E Stoops, K Goozee… - Translational …, 2021 - nature.com
Glial fibrillary acidic protein (GFAP), an astrocytic cytoskeletal protein, can be measured in
blood samples, and has been associated with Alzheimer's disease (AD). However, plasma …

Influence of the neuroprotective properties of quercetin on regeneration and functional recovery of the nervous system

SOM Fideles, A de Cássia Ortiz, DV Buchaim… - Antioxidants, 2023 - mdpi.com
Quercetin is a dietary flavonoid present in vegetables, fruits, and beverages, such as onions,
apples, broccoli, berries, citrus fruits, tea, and red wine. Flavonoids have antioxidant and anti …

[HTML][HTML] Blocking immune cell infiltration of the central nervous system to tame Neuroinflammation in Amyotrophic lateral sclerosis

S Garofalo, G Cocozza, G Bernardini, J Savage… - Brain, behavior, and …, 2022 - Elsevier
Neuroinflammation is one of the main hallmarks of amyotrophic lateral sclerosis (ALS).
Recently, peripheral immune cells were discovered as pivotal players that promptly …

[HTML][HTML] Ferroptosis is involved in hypoxic-ischemic brain damage in neonatal rats

W Lin, T Zhang, J Zheng, Y Zhou, Z Lin, X Fu - Neuroscience, 2022 - Elsevier
Ferroptosis is an iron-dependent form of regulated cell death, which is driven by loss of
activity of the lipid repair enzyme glutathione peroxidase 4 (GPX4) and subsequent …

[HTML][HTML] Glymphatic drainage blocking aggravates brain edema, neuroinflammation via modulating TNF-α, IL-10, and AQP4 after intracerebral hemorrhage in rats

X Liu, G Wu, N Tang, L Li, C Liu, F Wang… - Frontiers in Cellular …, 2021 - frontiersin.org
Objective The “Glymphatic” system, a network of perivascular tunnels wrapped by astrocyte
endfeet, was reported to be closely associated with the diseases of the central nervous …

[HTML][HTML] A hydrogel spinal dural patch with potential anti-inflammatory, pain relieving and antibacterial effects

J Li, J Tian, C Li, L Chen, Y Zhao - Bioactive materials, 2022 - Elsevier
CSFL caused by spinal dural defect is a common complication of spinal surgery, which need
repair such as suture or sealants. However, low intracranial pressure symptoms, wound …

Association of serum neurofilament light chain and glial fibrillary acidic protein levels with cognitive decline in Parkinson's disease

S Mao, X Teng, Z Li, J Zu, T Zhang, C Xu, G Cui - Brain Research, 2023 - Elsevier
Objectives To investigate whether serum neurofilament light chain (NfL) and glial fibrillary
acidic protein (GFAP) levels are associated with motor and cognitive function in Parkinson's …

Cisplatin-induced activation and functional modulation of satellite glial cells lead to cytokine-mediated modulation of sensory neuron excitability

M Leo, LI Schmitt, A Kutritz, C Kleinschnitz… - Experimental …, 2021 - Elsevier
Cisplatin plays an essential role in the treatment of various cancers. Cisplatin exhibits high
efficacy, but it often leads to severe neurotoxic side effects, such as chemotherapy-induced …