The gut microbiome plays critical roles in human health and disease. Recent studies
suggest it may also be associated with chronic pain and postoperative pain outcomes. In …

A spectrum of NCD exists in surgical patients ranging from postoperative delirium, delayed
neurocognitive recovery, and POCD. Identification of patients at-risk for developing NCD can …

Spouses of Alzheimer's disease (AD) patients are at a higher risk of developing incidental
dementia. However, the causes and underlying mechanism of this clinical observation …

Surgical pain is associated with delirium in patients, and acupuncture can treat pain.
However, whether electroacupuncture can attenuate the surgical pain-associated delirium …

Aims: Post-operative cognitive dysfunction (POCD) is the decline in cognitive function of the
central nervous system (CNS) after anesthesia/surgery. The present study explored whether …

Background Inflammation is considered a key factor in the development of postoperative
cognitive dysfunction (POCD). Therefore, we hypothesized that pre-operative anti …

With the aging of the world population, and improvements in medical and health
technologies, there are increasing numbers of elderly patients undergoing anaesthesia and …

Perioperative neurocognitive disorder (PND) is a common surgery outcome affecting up to a
third of the elderly patients, and it is associated with high morbidity and increased risk for …

Objective: To investigate gut microbiota and intestinal barrier function changes after
orthopedic surgery in elderly patients with either normal cognition (NC) or a prodromal …

Postoperative delirium is a common postoperative complication in older patients, and its
pathogenesis and biomarkers remain largely undetermined. The gut microbiota has been …