Enormous progress has been made in the last half-century in the management of diseases
closely integrated with excess body weight, such as hypertension, adult-onset diabetes and …

Background Pharmacotherapy provides an option for adults with overweight and obesity to
reduce their bodyweight if lifestyle modifications fail. We summarised the latest evidence for …

Background The long-term efficacy and safety of time-restricted eating for weight loss are not
clear. Methods We randomly assigned 139 patients with obesity to time-restricted eating …

Importance The effect of continuing vs withdrawing treatment with semaglutide, a glucagon-
like peptide 1 receptor agonist, on weight loss maintenance in people with overweight or …

The prevalence of heart failure is on the rise and imposes a major health threat, in part, due
to the rapidly increased prevalence of overweight and obesity. To this point …

Aims Obesity is a global health problem, associated with significant morbidity and mortality,
often due to cardiovascular (CV) diseases. While bariatric surgery is increasingly performed …

Obesity is a complex, chronic disease and global public health challenge. Characterized by
excessive fat accumulation in the body, obesity sharply increases the risk of several …

Obesity contributes to reduced life expectancy, impaired quality of life, and disabilities,
mainly in those individuals who develop cardiovascular diseases, type 2 diabetes …

Background Cagrilintide, a long-acting amylin analogue, and semaglutide 2· 4 mg, a
glucagon-like peptide-1 analogue, are both being investigated as options for weight …

China has one of the largest populations with obesity in the world, and obesity has become
a major challenge for the country's health-care system. Current guidelines for obesity …