BackgroundMajor depression (MD) is a risk factor for cardiovascular disease. Reduced
heart rate variability (HRV) has been observed in MD. Given the predictive value of HRV for …

There is a growing body of literature that recognizes the positive effects of exercise on mood
states such as anxiety, stress and depression, through physiological and biochemical …

Stress-linked psychiatric disorders, including anxiety and major depressive disorder, are
associated with systemic inflammation. Recent studies have reported stress-induced …

β-Endorphins are peptides that exert a wide variety of effects throughout the body. Produced
through the cleavage pro-opiomelanocortin (POMC), β-endorphins are the primarily agonist …

Prevalence, symptoms, and treatment of depression suggest that major depressive
disorders (MDD) present sex differences. Social stress-induced neurovascular pathology is …

Depression in bipolar disorder (BD) patients presents major clinical challenges. As the
predominant psychopathology even in treated BD, depression is associated not only with …

Background Depression is a nontraditional risk factor for cardiovascular disease (CVD).
Data on the association of depression and poor mental health with CVD and suboptimal …

Populations with common physical diseases–such as cardiovascular diseases, cancer and
neurodegenerative disorders–experience substantially higher rates of major depressive …

Chronic stress refers to the non-specific systemic reaction that occurs when the body is
stimulated by various internal and external negative factors over a long time. The …

Cardiovascular disease and brain disorders, such as depression and cognitive dysfunction,
are highly prevalent conditions and are among the leading causes limiting patient's quality …