Abstract Cyclooxygenase‐2 (COX‐2) is frequently expressed in many types of cancers
exerting a pleiotropic and multifaceted role in genesis or promotion of carcinogenesis and …

Cyclooxygenase‐2 (COX‐2) is an inducible form of the enzyme that catalyses the synthesis
of prostanoids, including prostaglandin E2 (PGE2), a major mediator of inflammation and …

Cyclooxygenase-2 isozyme is a promising anti-inflammatory drug target, and
overexpression of this enzyme is also associated with several cancers and …

Oral squamous cell carcinoma (OSCC) is the most common tumour of the oral cavity,
associated with significant morbidity and mortality. It is a multifactorial condition, both genetic …

Cancer management has undergone significant improvements, which led to increased long-
term survival rates among cancer patients. Radiotherapy (RT) has an important role in the …

Inflammation is a biological function which triggered after the mechanical tissue disruption or
from the responses by the incidence of physical, chemical or biological negotiator in body …

Recently, the focus of enhancing tumor radiosensitivity has shifted from chemotherapeutics
to targeted therapies. Cyclin-dependent kinase 4 and 6 (CDK4/6) inhibitors are a novel class …

Anti-psychotic medications are widely used to treat schizophrenia and bipolar disorder.
Besides their medical applications, anti-psychotic drugs have other pharmacological …

Radiotherapy alone or in combination with chemotherapy/surgery is widely used for
treatment of cancers. It reduces tumor growth and prevents metastasis. While ionizing …

Human cardiac fibroblasts (HCFs) play key roles in normal physiological functions and
pathological processes in the heart. Our recent study has found that, in HCFs, sphingosine 1 …