The endoplasmic reticulum (ER) is a multifunctional organelle responsible for production of
both lumenal and membrane components of secretory pathway compartments. Secretory …

The composition of phospholipids, sphingolipids, and sterols in the plasma membrane has a
strong influence on the activity of the proteins associated or embedded in the lipid bilayer …

The yeast Saccharomyces cerevisiae, with its full complement of organelles, synthesizes
membrane phospholipids by pathways that are generally common to those found in higher …

The oleaginous yeast Yarrowia lipolytica can accumulate up to 38% of its dry weight (DW)
as lipids. Factors involved in lipid accumulation, particularly triglycerides, are not well …

During the past two decades invasive fungal infections have emerged as major causes of
morbidity and mortality in immunocompromised patients. Several factors have contributed to …

During energy bursts, neutral lipids fabricated within the ER bilayer demix to form lipid
droplets (LDs). LDs bud off mainly in the cytosol where they regulate metabolism and …

A cDNA encoding myo-inositol O-methyltransferase (IMT1) has been transferred into
Nicotiana tabacum cultivar SR1. During drought and salt stress, transformants (I5A) …

A basic feature of eukaryotic cells is that they contain a nucleus and numerous distinctive
membrane-bounded organelles within the cytoplasm. Prominent among these intracellular …

The current status of the biochemistry of phospholipid biosynthesis is presented. The review
focuses on the identification and characterization of molecular tools such as purified …

Life-like systems need to maintain a basal metabolism, which includes importing a variety of
building blocks required for macromolecule synthesis, exporting dead-end products, and …