Biosensors for healthcare: Current and future perspectives

ER Kim, C Joe, RJ Mitchell, MB Gu - Trends in Biotechnology, 2023 - cell.com
Biosensors are utilized in several different fields, including medicine, food, and the
environment; in this review, we examine recent developments in biosensors for healthcare …

[HTML][HTML] Aptamer-based CRISPR-Cas powered diagnostics of diverse biomarkers and small molecule targets

US Kadam, Y Cho, TY Park, JC Hong - Applied Biological Chemistry, 2023 - Springer
CRISPR-Cas systems have been widely used in genome editing and transcriptional
regulation. Recently, CRISPR-Cas effectors are adopted for biosensor construction due to its …

Nanomedicine for Diagnosis and Treatment of Atherosclerosis

J Cheng, H Huang, Y Chen, R Wu - Advanced Science, 2023 - Wiley Online Library
With the changing disease spectrum, atherosclerosis has become increasingly prevalent
worldwide and the associated diseases have emerged as the leading cause of death. Due …

CRISPR/Cas systems accelerating the development of aptasensors

C Zhu, F Zhang, H Li, Z Chen, M Yan, L Li… - TrAC Trends in Analytical …, 2023 - Elsevier
The clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-
associated proteins (CRISPR/Cas) systems, regarded as “God's scissors”, have recently …

Nanomaterials driven CRISPR/Cas-based biosensing strategies

Y Huang, Q Wen, Y Xiong, Y Chen, W Li, J Ren… - Chemical Engineering …, 2023 - Elsevier
The advancement of biosensing has led to increased demands for precise target recognition
and highly sensitive detection. Nanomaterials have emerged as indispensable contributors …

CRISPR/Cas12-based electrochemical biosensors for clinical diagnostic and food monitoring

CY Kharismasari, MIHL Zein, A Hardianto… - …, 2023 - Elsevier
Each organism has a unique sequence of nitrogenous bases in in the form of DNA or RNA
which distinguish them from other organisms. This characteristic makes nucleic acid-based …

[HTML][HTML] Recent advances in CRISPR/Cas-Based biosensors for protein detection

J Wang, X Yang, X Wang, W Wang - Bioengineering, 2022 - mdpi.com
CRISPR is an acquired immune system found in prokaryotes that can accurately recognize
and cleave foreign nucleic acids, and has been widely explored for gene editing and …

A CRISPR-Cas12a-based electrochemical biosensor for the detection of microphthalmia-associated transcription factor

Q Luo, C Zhang, X Deng, D Liu, X Pan, Y Gong… - Microchimica Acta, 2024 - Springer
A novel electrochemical biosensor that combines the CRISPR-Cas12a system with a gold
electrode is reported for the rapid and sensitive detection of microphthalmia-associated …

Multiplex strategy electrochemical platform based on self-assembly dual-site DNA tetrahedral scaffold for one-step detection of diazinon and profenofos

G Wang, J Sun, B Li, F Guan, J Huang, H Dong… - Science of The Total …, 2023 - Elsevier
In the work, based on self-assembly dual-site DNA tetrahedral scaffold (DTS), thionine (Thi),
and 6-(Ferrocenyl) hexanethiol (Fc6S), a multiplex strategy electrochemical platform was …

Recent progress in aptamer and CRISPR-Cas12a based systems for non-nucleic target detection

R Yang, L Zhao, X Wang, W Kong… - Critical Reviews in …, 2023 - Taylor & Francis
Efficient and sensitive detection of targets is one of the motivations for constant development
and innovation of various biosensors. CRISPR-Cas12a, a new generation of gene editing …