A large proportion of ICU-acquired infections are related to multidrug-resistant bacteria
(MDR). Infections caused by these bacteria are associated with increased mortality, and …

Background COVID-19 patients requiring mechanical ventilation are particularly at risk of
developing ventilator-associated pneumonia (VAP). Risk factors and the prognostic impact …

Introduction Lower respiratory tract infections are amongst the main causes for
hospital/intensive care unit admissions and antimicrobial prescriptions. In order to reduce …

OBJECTIVES: To determine the impact of high doses of corticosteroids (HDCT) in critically ill
COVID-19 patients with nonresolving acute respiratory distress syndrome (ARDS) who had …

Background Ventilator‐associated lower respiratory tract infections (VA‐LRTI) increase
morbidity and mortality in intensive care unit (ICU) patients. Higher incidences of VA‐LRTI …

Corticosteroids represent a major tool for the treatment and management of infection due to
severe to acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Multiple large platform …

Purpose Patients presenting the most severe form of coronavirus disease 2019 (COVID-19)
pneumonia, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

Purpose The aim of this study is to design a population pharmacokinetic study to gain a
deeper understanding of the pharmacokinetics of dexamethasone in critically ill COVID-19 …

We read with interest Shorr and Zilberberg [1] about the association between ventilator-
associated pneumonia (VAP) and corticosteroid treatment for COVID-19 respiratory failure …

In their recent comment, Shorr and Zilberberg registered concerns about the analysis
performed concerning the association of Ventilator-associated pneumonia (VAP) and …