The walking dead: macrophage inflammation and death in atherosclerosis

MM Kavurma, KJ Rayner… - Current opinion in …, 2017 - journals.lww.com
The walking dead: macrophage inflammation and death in ather... : Current Opinion in
Lipidology The walking dead: macrophage inflammation and death in atherosclerosis : Current …

The in vivo evidence for regulated necrosis

W Tonnus, A Linkermann - Immunological reviews, 2017 - Wiley Online Library
Necrosis is a hallmark of several widespread diseases or their direct complications. In the
past decade, we learned that necrosis can be a regulated process that is potentially …

[HTML][HTML] RIP1/RIP3-regulated necroptosis as a target for multifaceted disease therapy

Y Liu, T Liu, T Lei, D Zhang, S Du… - International …, 2019 - spandidos-publications.com
Necroptosis is a type of programmed cell death with necrotic morphology, occurring in a
variety of biological processes, including inflammation, immune response, embryonic …

Regulation of NKT cell-mediated immune responses to tumours and liver inflammation by mitochondrial PGAM5-Drp1 signalling

YJ Kang, BR Bang, KH Han, L Hong, EJ Shim… - Nature …, 2015 - nature.com
The receptor-interacting protein kinase 3 (RIPK3) plays crucial roles in programmed
necrosis and innate inflammatory responses. However, a little is known about the …

Resolvin D1 enhances necroptotic cell clearance through promoting macrophage fatty acid oxidation and oxidative phosphorylation

Z Hosseini, M Marinello, C Decker… - … , and vascular biology, 2021 - Am Heart Assoc
Objective: Plaque necrosis is a key feature of defective resolution in atherosclerosis. Recent
evidence suggests that necroptosis promotes plaque necrosis; therefore, we sought to …

Programmed necrosis in heart disease: molecular mechanisms and clinical implications

H Zhu, A Sun - Journal of molecular and cellular cardiology, 2018 - Elsevier
Programmed cell death plays an essential role in myocardial homeostasis and pathology.
Three distinct forms of programmed cell death have been identified, namely apoptosis …

RIPK1 inhibitor Cpd-71 attenuates renal dysfunction in cisplatin-treated mice via attenuating necroptosis, inflammation and oxidative stress

J Wang, M Liu, F Wang, B Wei, Q Yang, Y Cai… - Clinical …, 2019 - portlandpress.com
Acute kidney injury (AKI) is a destructive clinical condition induced by multiple insults
including ischemic reperfusion, nephrotoxic drugs and sepsis. It is characterized by a …

Macrophage biology in cardiovascular diseases

MK Khoury, H Yang, B Liu - Arteriosclerosis, thrombosis, and …, 2021 - Am Heart Assoc
Macrophages have a key functional role in the pathogenesis of various cardiovascular
diseases, such as atherosclerosis and aortic aneurysms. Their accumulation within the …

Regulation of Csf1r and Bcl6 in Macrophages Mediates the Stage-Specific Effects of MicroRNA-155 on Atherosclerosis

Y Wei, M Zhu, J Corbalán-Campos, K Heyll… - … , and vascular biology, 2015 - Am Heart Assoc
Objective—The function of microRNAs is highly context and cell type dependent because of
their highly dynamic expression pattern and the regulation of multiple mRNA targets …

Atorvastatin inhibits pyroptosis through the lncRNA NEXN-AS1/NEXN pathway in human vascular endothelial cells

LM Wu, SG Wu, F Chen, Q Wu, CM Wu, CM Kang, X He… - Atherosclerosis, 2020 - Elsevier
Background and aims Many clinical trials have demonstrated that statins convey protective
effects against atherosclerosis independent of cholesterol-lowering capacities. Other …