[HTML][HTML] Increase in acid sphingomyelinase level in human retinal endothelial cells and CD34+ circulating angiogenic cells isolated from diabetic individuals is …

N Kady, Y Yan, T Salazar, Q Wang… - Journal of clinical …, 2017 - Elsevier
Background Diabetic retinopathy is a microvascular disease that results from retinal vascular
degeneration and defective repair due to diabetes-induced endothelial progenitor …

Combined intravitreal ranibizumab and oral supplementation with docosahexaenoic acid and antioxidants for diabetic macular edema: Two-year randomized single …

M Lafuente, L Ortín, M Argente, JL Guindo… - Retina, 2017 - journals.lww.com
Purpose: To assess the 2-year effectiveness of intravitreal ranibizumab combined with a
dietary supplement rich in docosahexaenoic acid (DHA) plus antioxidants in 62 patients with …

Mitochondrial ceramide effects on the retinal pigment epithelium in diabetes

Y Levitsky, SS Hammer, KP Fisher, C Huang… - International Journal of …, 2020 - mdpi.com
Mitochondrial damage in the cells comprising inner (retinal endothelial cells) and outer
(retinal pigment epithelium (RPE)) blood–retinal barriers (BRB) is known to precede the …

[HTML][HTML] Hematopoietic stem/progenitor involvement in retinal microvascular repair during diabetes: Implications for bone marrow rejuvenation

AD Bhatwadekar, Y Duan, M Korah, JS Thinschmidt… - Vision research, 2017 - Elsevier
The widespread nature of diabetes affects all organ systems of an individual including the
bone marrow. Long-term damage to the cellular and extracellular components of the bone …

Alteration of erythrocyte membrane polyunsaturated fatty acids in preterm newborns with retinopathy of prematurity

C Pallot, J Mazzocco, C Meillon, DS Semama… - Scientific Reports, 2019 - nature.com
Extremely preterm infants are at high risk for retinopathy of prematurity (ROP), a potentially
blinding disease characterized by abnormalities in retinal vascularization. Whereas animal …

Is fish oil a potential treatment for diabetic peripheral neuropathy?

MA Yorek - Current diabetes reviews, 2018 - ingentaconnect.com
Background: Peripheral neuropathy affects about 50% of the diabetic population. The
manifestations range from pain, numbness, paresthesia and ulceration in the extremities …

Direct and maternal n-3 long-chain polyunsaturated fatty acid supplementation improved triglyceridemia and glycemia through the regulation of hepatic and muscle …

F Kasbi-Chadli, V Ferchaud-Roucher, M Krempf… - European journal of …, 2016 - Springer
Purpose We recently reported that direct and maternal supplementation with n-3 long-chain
polyunsaturated fatty acids (n-3 LC-PUFA) alleviates the metabolic disturbances in adult …

[HTML][HTML] Omega-3 Polyunsaturated Fatty Acids and Their Anti-Oxidant, Anti-Inflammatory and Neuroprotective Effects in Diabetic Retinopathy: A Narrative Review

S Fathima, E Prokopiou, T Georgiou - Frontiers in Bioscience …, 2023 - imrpress.com
Diabetic retinopathy (DR) is a common microvascular complication of type 2 Diabetes
Mellitus (T2DM) that can have vision-threatening consequences, particularly if it advances to …

Understanding the Impact of Polyunsaturated Fatty Acids on Age-Related Macular Degeneration: A Review

M Brito, C Sorbier, N Mignet, V Boudy… - International Journal of …, 2024 - mdpi.com
Age-related Macular Degeneration (AMD) is a multifactorial ocular pathology that destroys
the photoreceptors of the macula. Two forms are distinguished, dry and wet AMD, with …

Glucose-mediated de novo lipogenesis in photoreceptors drives early diabetic retinopathy

R Rajagopal, B Sylvester, S Zhang, S Adak… - Journal of Biological …, 2021 - ASBMB
Diabetic retinopathy (DR) is an increasingly frequent cause of blindness across populations;
however, the events that initiate pathophysiology of DR remain elusive. Strong preclinical …