Background SARS-CoV-2 infection causes acute respiratory distress, which may progress to
multiorgan failure and death. Severe COVID-19 disease is accompanied by reduced …

Preterm infants are at increased risk for invasive neonatal bacterial infections. S.
epidermidis, a ubiquitous skin commensal, is a major cause of late-onset neonatal sepsis …

Nonimmune cells can have immunomodulatory roles that contribute to healthy development.
However, the molecular and cellular mechanisms underlying the immunomodulatory …

Knowledge of the mechanisms underpinning the development of protective immunity
conferred by mRNA vaccines is fragmentary. Here, we investigated responses to …

Background Immune checkpoint inhibitors (ICIs) have revolutionized the treatment of cancer.
However, only a portion of patients respond to such treatments. Therefore, it remains a …

Red blood cells (RBCs) have traditionally been seen as simple carriers of gases and
nutrients in the body. One important non‐canonical function of RBCs in the cardiovascular …

Psoriasis is one of the most common inflammatory skin diseases with a chronic, relapsing-
remitting course. The last decades of intense research uncovered a pathological network of …

Recent studies have demonstrated that a particular group of nucleated cells that exhibit
erythroid markers (TER119 in mice and CD235a in humans) possess the ability to suppress …

Erythrocytes are the most abundant type of cells in the blood and have a relatively simple
structure when mature; they have a long life-span in the circulatory system. The primary …

Abstract CD71+ erythroid cells (CECs) have been recently recognized in both neonates and
cancer patients as potent immunoregulatory cells. Here, we show that in mice early-stage …