Bone tissue engineering for treating osteonecrosis of the femoral head

Y Bian, T Hu, Z Lv, Y Xu, Y Wang, H Wang, W Zhu… - …, 2023 - Wiley Online Library
Osteonecrosis of the femoral head (ONFH) is a devastating and complicated disease with an
unclear etiology. Femoral head‐preserving surgeries have been devoted to delaying and …

[HTML][HTML] Multiphasic scaffolds for the repair of osteochondral defects: outcomes of preclinical studies

R Chen, JS Pye, J Li, CB Little, JJ Li - Bioactive Materials, 2023 - Elsevier
Osteochondral defects are caused by injury to both the articular cartilage and subchondral
bone within skeletal joints. They can lead to irreversible joint damage and increase the risk …

Polysaccharide-bioceramic composites for bone tissue engineering: A review

PM Sivakumar, AA Yetisgin, E Demir, SB Sahin… - International Journal of …, 2023 - Elsevier
Limitations associated with conventional bone substitutes such as autografts, increasing
demand for bone grafts, and growing elderly population worldwide necessitate development …

Development of biomimetic electrospun polymeric biomaterials for bone tissue engineering. A review

S Chahal, A Kumar, FSJ Hussian - Journal of biomaterials science …, 2019 - Taylor & Francis
Electrospinning is a promising and versatile technique that is used to fabricate polymeric
nanofibrous scaffolds for bone tissue engineering. Ideal scaffolds should be biocompatible …

Current approaches to bone tissue engineering: the interface between biology and engineering

JJ Li, M Ebied, J Xu, H Zreiqat - Advanced healthcare materials, 2018 - Wiley Online Library
The successful regeneration of bone tissue to replace areas of bone loss in large defects or
at load‐bearing sites remains a significant clinical challenge. Over the past few decades …

Mineralization of biomaterials for bone tissue engineering

X Wu, K Walsh, BL Hoff, G Camci-Unal - Bioengineering, 2020 - mdpi.com
Mineralized biomaterials have been demonstrated to enhance bone regeneration compared
to their non-mineralized analogs. As non-mineralized scaffolds do not perform as well as …

Bioglass® 45S5‐based composites for bone tissue engineering and functional applications

M Rizwan, M Hamdi, WJ Basirun - Journal of biomedical …, 2017 - Wiley Online Library
Abstract Bioglass® 45S5 (BG) has an outstanding ability to bond with bones and soft
tissues, but its application as a load‐bearing scaffold material is restricted due to its inherent …

Bilayered PLGA/PLGA-HAp composite scaffold for osteochondral tissue engineering and tissue regeneration

X Liang, P Duan, J Gao, R Guo, Z Qu, X Li… - ACS Biomaterials …, 2018 - ACS Publications
This study is aimed at investigation of the osteochondral regeneration potential of bilayered
PLGA/PLGA-HAp composite scaffolds with one layer made of biodegradable polymer poly …

Extracellular vesicles-loaded DNA hydrogels: a promising candidate for cartilage organoids engineering

Z Ma, Y Wu, G Li, J Liu, Z Geng, J Su - Chemical Engineering Journal, 2023 - Elsevier
Articular cartilage lesion such as osteoarthritis (OA) is becoming a serious threat to global
human health. In recent years, as a new paradigm in cartilage tissue engineering and …

In-vitro and in-vivo studies of PLA/PCL/gelatin composite scaffold containing ascorbic acid for bone regeneration

SF Hashemi, M Mehrabi, A Ehterami… - Journal of Drug Delivery …, 2021 - Elsevier
Bone cells require solid support similar to the extracellular matrix networks for repairing
damaged areas of the bone. Selecting materials and manufacturing process of scaffold is a …