It is now well established that increased programmed death-1-ligand 1 (PD-L1) surface
expression in cancer cells and the resultant T cell suppression contribute to cancer cell …

Objective: Survival after resections for non-small cell lung cancer remains poor. Recurrent
lung cancer remains common. Due to the common risk factor of smoking, cardiovascular …

Abstract Cyclooxygenase-2 (COX-2), an enzyme that catalyzes the synthesis of
prostaglandins, is made inducible by various stimuli such as inflammation. Although COX-2 …

Studies have conjectured that nonsteroidal anti-inflammatory drugs (NSAID) inhibit growth of
various malignancies by inhibiting cyclooxygenase-2 (COX-2) enzyme activity. Yet, several …

Objective (s): Combination chemotherapy is a rational strategy to increase patient response
and tolerability and to decrease adverse effects and drug resistance. Recently, the use of …

BACKGROUND: Although malignant pleural mesothelioma is a rare tumour, its incidence is
increasing. The prognosis remains very poor with an average survival of 10 months from …

Increasing evidence suggests a role for cyclooxygenase‐2 (COX‐2) in traumatic brain injury
(TBI). In the present study, the role of COX‐2 in TBI was investigated using COX‐2 gene …

Endometrial carcinoma (EC) ranks as the most common female genital cancer in developed
countries. Lately, more and more long noncoding RNAs (lncRNAs) have been identified as …

ABSTRACT Heme oxygenase-1 (HO-1) is a stress-inducible rate-limiting enzyme in heme
degradation that confers cytoprotection against oxidative injury and performs a vital function …