Loss-of-function mutations in the MID1 gene cause a rare monogenic disorder, Opitz BBB/G
syndrome (OS), which is characterized by malformations of the ventral midline. The MID1 …

It should be noted that 3-phosphoinositide-dependent protein kinase-1 (PDK1) is a protein
encoded by the PDPK1 gene, which plays a key role in the signaling pathways activated by …

Despite the great advances in target therapy, lung cancer remains the top cause of cancer-
related death worldwide. G protein-coupled receptor neurokinin-1 (NK1R) is shown to play …

Head and neck squamous cell carcinoma (HNSCC) patients have a poor prognosis, with
invasion and metastasis as major causes of mortality. The phosphatidylinositol 3-kinase …

Many natural compounds derived from plants or microbes show promising potential for
anticancer treatment, but few have been found to target energy-relevant regulators. In this …

Background Recent genomic evidence suggests frequent phosphatidylinositide 3-kinase
(PI3K) pathway activation in human papillomavirus (HPV) positive oropharyngeal squamous …

HPV-positive oropharyngeal cancer patients experience significantly lower locoregional
recurrence and higher overall survival in comparison with HPV-negative patients, especially …

BACKGROUND: It is of great clinical significance to discover novel biomarkers for neck
squamous cell carcinoma (HNSCC) treatments. We discovered a potential cancer-related …

Abnormal expression of microRNAs (miRNAs) contributes to tumour growth and invasion.
MiR-326 expression often down-regulates in several kinds of cancer and low expression of …

Wei Y, Liao Y, Deng Y, Zu Y, Zhao B, Li F. Onco Targets Ther. 2019; 12: 9005–9016. We, the
Editors and Publisher of OncoTargets and Therapy, have retracted the following article …