[PDF][PDF] The MID1 protein is a central player during development and in disease
J Winter, MF Basilicata, MP Stemmler… - … Biosci (Landmark Ed), 2016 - article.imrpress.com
Loss-of-function mutations in the MID1 gene cause a rare monogenic disorder, Opitz BBB/G
syndrome (OS), which is characterized by malformations of the ventral midline. The MID1 …
syndrome (OS), which is characterized by malformations of the ventral midline. The MID1 …
3-Phosphoinositide-dependent protein kinase-1 as an emerging target in the management of breast cancer
C Fyffe, M Falasca - Cancer management and research, 2013 - Taylor & Francis
It should be noted that 3-phosphoinositide-dependent protein kinase-1 (PDK1) is a protein
encoded by the PDPK1 gene, which plays a key role in the signaling pathways activated by …
encoded by the PDPK1 gene, which plays a key role in the signaling pathways activated by …
Neurokinin-1 receptor promotes non-small cell lung cancer progression through transactivation of EGFR
XW Zhang, L Li, WQ Hu, MN Hu, Y Tao, H Hu… - Cell Death & …, 2022 - nature.com
Despite the great advances in target therapy, lung cancer remains the top cause of cancer-
related death worldwide. G protein-coupled receptor neurokinin-1 (NK1R) is shown to play …
related death worldwide. G protein-coupled receptor neurokinin-1 (NK1R) is shown to play …
Overexpression of PIK3CA in murine head and neck epithelium drives tumor invasion and metastasis through PDK1 and enhanced TGFβ signaling
L Du, X Chen, Y Cao, L Lu, F Zhang, S Bornstein, Y Li… - Oncogene, 2016 - nature.com
Head and neck squamous cell carcinoma (HNSCC) patients have a poor prognosis, with
invasion and metastasis as major causes of mortality. The phosphatidylinositol 3-kinase …
invasion and metastasis as major causes of mortality. The phosphatidylinositol 3-kinase …
Neoalbaconol induces energy depletion and multiple cell death in cancer cells by targeting PDK1-PI3-K/Akt signaling pathway
Q Deng, X Yu, L Xiao, Z Hu, X Luo, Y Tao, L Yang… - Cell Death & …, 2013 - nature.com
Many natural compounds derived from plants or microbes show promising potential for
anticancer treatment, but few have been found to target energy-relevant regulators. In this …
anticancer treatment, but few have been found to target energy-relevant regulators. In this …
PIK3CA, HRAS and PTEN in human papillomavirus positive oropharyngeal squamous cell carcinoma
Background Recent genomic evidence suggests frequent phosphatidylinositide 3-kinase
(PI3K) pathway activation in human papillomavirus (HPV) positive oropharyngeal squamous …
(PI3K) pathway activation in human papillomavirus (HPV) positive oropharyngeal squamous …
[HTML][HTML] HPV-associated differential regulation of tumor metabolism in oropharyngeal head and neck cancer
YS Jung, AJ Najy, W Huang, S Sethi, M Snyder… - Oncotarget, 2017 - ncbi.nlm.nih.gov
HPV-positive oropharyngeal cancer patients experience significantly lower locoregional
recurrence and higher overall survival in comparison with HPV-negative patients, especially …
recurrence and higher overall survival in comparison with HPV-negative patients, especially …
Potential roles of Cornichon Family AMPA Receptor Auxiliary Protein 4 (CNIH4) in head and neck squamous cell carcinoma
H Liu, Y Li - Cancer Biomarkers, 2022 - content.iospress.com
BACKGROUND: It is of great clinical significance to discover novel biomarkers for neck
squamous cell carcinoma (HNSCC) treatments. We discovered a potential cancer-related …
squamous cell carcinoma (HNSCC) treatments. We discovered a potential cancer-related …
Gold nano-particles (AuNPs) carrying miR-326 targets PDK1/AKT/c-myc axis in hepatocellular carcinoma
Y Mo, L He, Z Lai, Z Wan, Q Chen, S Pan… - Artificial Cells …, 2019 - Taylor & Francis
Abnormal expression of microRNAs (miRNAs) contributes to tumour growth and invasion.
MiR-326 expression often down-regulates in several kinds of cancer and low expression of …
MiR-326 expression often down-regulates in several kinds of cancer and low expression of …
RETRACTED ARTICLE: MicroRNA-503 Inhibits Non-Small Cell Lung Cancer Progression By Targeting PDK1/PI3K/AKT Pathway
Y Wei, Y Liao, Y Deng, Y Zu, B Zhao… - OncoTargets and …, 2019 - Taylor & Francis
Wei Y, Liao Y, Deng Y, Zu Y, Zhao B, Li F. Onco Targets Ther. 2019; 12: 9005–9016. We, the
Editors and Publisher of OncoTargets and Therapy, have retracted the following article …
Editors and Publisher of OncoTargets and Therapy, have retracted the following article …