Emerging Trends in Bilosomes as Therapeutic Drug Delivery Systems

H Kaurav, M Tripathi, SD Kaur, A Bansal, DN Kapoor… - Pharmaceutics, 2024 - mdpi.com
In recent years, there has been a notable surge in the utilization of stabilized bile acid
liposomes, chemical conjugates, complexes, mixed micelles, and other drug delivery …

Formulation development and in vitro/in vivo characterization of methotrexate-loaded nanoemulsion gel formulations for enhanced topical delivery

MS Latif, A Nawaz, M Asmari, J Uddin, H Ullah… - Gels, 2022 - mdpi.com
Methotrexate-loaded oil-in-water nanoemulsion formulations were prepared using the high
shear homogenization technique. A drug excipient study (ATR-FTIR) was carried out to …

A novel reverse micelle based cationic double nanoemulsion as a potential nanoplatform for enhancing the anitglucomal activity of betaxolol hydrochloride; …

MG Sakr, SA El-Zahaby, AM Al-Mahallawi… - Journal of Drug Delivery …, 2023 - Elsevier
Glaucoma is one of the most common causes of irreversible vision loss worldwide. The
hydrophilic nature of the anti-glaucoma drug Betaxolol hydrochloride (BH) limits its ocular …

Exploitation of transdermal nanobilosomal gel platforms for ameliorating anti-diabetic activity of empagliflozin following I-optimal design

TM Ibrahim - Journal of Drug Delivery Science and Technology, 2023 - Elsevier
The current study aimed to optimize a bilosomal gel (bilo-gel) formulation loaded with anti-
diabetic empagliflozin. Enhancement of transdermal delivery of empagliflozin was targeted …

Ion-Triggered In Situ Gelling Intranasal Spray of Dronedarone Hydrochloride Nanocarriers: In Vitro Optimization and In Vivo Pharmacokinetic Appraisal

MH Teaima, DA Helal, JM Alsofany, MA El-Nabarawi… - Pharmaceutics, 2022 - mdpi.com
The current study aims to develop niosomal nanocarriers for intranasal delivery of
dronedarone hydrochloride to ameliorate its limited bioavailability. Niosomes were prepared …

Novel Vesicular Bilosomal Delivery Systems for Dermal/Transdermal Applications

V Suvarna, R Mallya, K Deshmukh… - Current Drug …, 2024 - ingentaconnect.com
The application of therapeutically active molecules through the dermal/transdermal route
into the skin has evolved as an attractive formulation strategy in comparison to oral delivery …

Development of nanobigel system combining apoptosis-inducing daidzein and flaxseed oil for the synergistic treatment of skin cancer

B Mangla, A Kaur, P Kumar, S Javed, W Ahsan… - Journal of Drug Delivery …, 2024 - Elsevier
Daidzein (DDZ), an isoflavone containing phytoestrogen, and flaxseed oil (FSO), an omega-
3-polyunsaturated fatty acid rich dietary lipid, are known to exert anticancer effects via …

Repurposing of Nano-Engineered Piroxicam as an Approach for Cutaneous Wound Healing

JM Alsofany, SE Khater - Journal of Pharmaceutical Sciences, 2024 - Elsevier
Drug repurposing is a potential strategy to overcome the huge economic expenses of wound
healing products. This work aims to develop a topical gel of piroxicam encapsulated into a …

Development of Transdermal Oleogel Containing Olmesartan Medoxomil: Statistical Optimization and Pharmacological Evaluation

RM El-Dahmy, I Elsayed, J Hussein, M Althubiti… - Pharmaceutics, 2023 - mdpi.com
Olmesartan medoxomil (OLM) is a first-line antihypertensive drug with low oral
bioavailability (28.6%). This study aimed to develop oleogel formulations to decrease OLM …

The Exploitation of Sodium Deoxycholate-Stabilized Nano-Vesicular Gel for Ameliorating the Antipsychotic Efficiency of Sulpiride

MH Abdallah, MM Shahien, A Alshammari, S Ibrahim… - Gels, 2024 - mdpi.com
The present study explored the effectiveness of bile-salt-based nano-vesicular carriers
(bilosomes) for delivering anti-psychotic medication, Sulpiride (Su), via the skin. A response …