Acute myocardial infarction (MI) inflicts massive injury to the coronary microcirculation
leading to vascular disintegration and capillary rarefication in the infarct region. Tissue …

The formation and accumulation of methylglyoxal (MGO), a highly reactive dicarbonyl
compound, has been implicated in the pathogenesis of type 2 diabetes, vascular …

Chronic wounds in diabetes undergo a lifetime risk of developing into diabetic foot ulcers.
Oxygen is crucial to wound healing by regulating cell proliferation, migration, and …

Ischemic disorders, such as myocardial infarction, stroke, and peripheral vascular disease,
are the most common causes of debilitating disease and death in westernized cultures. The …

There is a pandemic of physical inactivity that appears to parallel the widespread
prevalence of cardiovascular disease (CVD). Yet, regular physical activity (PA) and exercise …

In contrast to the general belief, endothelial cell (EC) metabolism has recently been
identified as a driver rather than a bystander effect of angiogenesis in health and disease …

Micro RNA s (mi RNA s) are small non‐coding RNA s that regulate gene expression at a
post‐transcriptional level via either the degradation or translational repression of a target …

A chronic wound in diabetic patients is usually characterized by poor angiogenesis and
delayed wound closure. The exploration of efficient strategy to significantly improve …

Epigenetic alterations occur in many physiological and pathological processes. N 6-
methyladenosine (m 6 A) modification is the most prevalent modification in eukaryotic …

Background Advanced glycation end-products (AGEs) are elevated under diabetic
conditions and associated with insulin resistance, endothelial dysfunction and vascular …