Peripheral neuropathies are characterized by nerves damage and axonal loss, and they
could be classified in hereditary or acquired forms. Acquired peripheral neuropathies are …

Microglia are the only resident innate immune cells derived from the mesoderm in the nerve
tissue. They play a role in the development and maturation of the central nervous system …

Abstract Background and Purpose Chronic pain is considered a key factor contributing to
alcohol use disorder (AUD). The mechanisms responsible for chronic pain associated with …

Neurons in the somatic, sympathetic, and parasympathetic ganglia are surrounded by
envelopes consisting of satellite glial cells (SGCs). Recently, it has become clear that SGCs …

In the most recent decades, oxaliplatin has been used as a chemotherapeutic agent for
colorectal cancer and other malignancies as well. Oxaliplatin interferes with tumor growth …

The increased presence of senescent cells in different neurological diseases suggests the
contribution of senescence in the pathophysiology of neurodegenerative disorders …

Oxaliplatin (OXA) is a common chemotherapy drug and exhibits clinical activity in several
cancer types. Its anticancer clinical effect is frequently accompanied by neurotoxicity. The …

Inflammatory pain is the perception of noxious stimuli that occurs during inflammation or an
immune response. Glial cells are widespread in the central and peripheral nervous systems …

Oxaliplatin-induced peripheral neuropathy (OIPN) is a serious side effect that impairs the
quality of life of patients treated with the chemotherapeutic agent, oxaliplatin. The underlying …

The clinical burden faced by chronic pain patients is compounded by affective comorbidities,
such as depression and anxiety disorders. Emerging evidence suggests that reactive glial …