Epithelial-to-mesenchymal transition (EMT) determines the most lethal features of cancer,
metastasis formation and chemoresistance, and therefore represents an attractive target in …

Background and Objectives: It is generally accepted that inflammatory cells found in the
tumor microenvironment are involved in the neoplastic process, promoting cell proliferation …

Simple Summary Inflammation is like the proverbial double-edged sword. Controlled short-
term inflammation could be a protective response while uncontrolled inflammation sustains …

The medicinal use of aspirin stretches back to ancient times, before it was manufactured in
its pure form in the late 19th century. Its accepted mechanistic target, cyclooxygenase (COX) …

Non-steroidal anti-inflammatory drugs (NSAIDs) are used extensively for analgesic and
antipyretic treatments. In addition, NSAIDs reduce the risk and mortality to several cancers …

Non‐small‐cell lung cancer (NSCLC) is a cancer with high morbidity and mortality. We
aimed to define the effect of Go‐Ichi‐Ni‐San complex subuint 2 (GINS2) acting on NSCLC …

Ursolic acid (UA), a natural pentacyclic triterpenoid carboxylic acid distributed in medical
herbs, exerts antitumor effects and is emerging as a promising compound for cancer …

Helicobacter pylori strains produce tumor necrosis factor‐α (TNF‐α)‐inducing protein, Tipα
as a carcinogenic factor in the gastric epithelium. Tipα acts as a homodimer with 38‐kDa …

Arctigenin (ARC) is a lignan that is abundant in Asteraceae plants, which show anti-
inflammatory and anti-cancer activities. The current study investigated whether ARC affects …

Transforming growth factor-ß1 (TGF-β1) is a multifunctional cytokine that is involved in
various pathophysiological processes, including cancer progression and fibrotic disorders …