Importance Prostate cancer is the most common cancer diagnosis made in men with more
than 160 000 new cases each year in the United States. Although it often has an indolent …

Importance Perirectal spacers are intended to lower the risk of rectal toxic effects associated
with prostate radiotherapy. A quantitative synthesis of typical clinical results with specific …

Purpose Men with localized prostate cancer often are treated with external radiotherapy (RT)
over 8 to 9 weeks. Hypofractionated RT is given over a shorter time with larger doses per …

Background Studies have reported a low α/β ratio for prostate cancer, suggesting that
hypofractionation could enhance the biological tumour dose without increasing …

Background External beam radiation therapy (EBRT) is a standard definitive treatment
option for men with localized prostate cancer and confers long-term prostate cancer control …

Purpose To report the final results on treatment outcomes of a randomized trial comparing
conventional and hypofractionated radiotherapy in high-risk, organ-confined prostate cancer …

As we mark 150 years since the birth of Marie Curie, we reflect on the global advances
made in radiation oncology and the current status of radiation therapy (RT) research. Large …

Background and purpose Multiple large trials have established the non-inferiority of
hypofractionated radiotherapy compared to conventional fractionation. This study will …

Purpose To compare toxicity rates in patients with localized prostate cancer treated with
standard fractionated external beam radiotherapy (EBRT) with or without an additional …

Background and purpose To explore the use of texture analysis (TA) features of patients' 3D
dose distributions to improve prediction modelling of treatment complication rates in prostate …