Sperm DNA fragmentation index as a promising predictive tool for male infertility diagnosis and treatment management–meta-analyses

D Santi, G Spaggiari, M Simoni - Reproductive biomedicine online, 2018 - Elsevier
Conventional semen analyses have limitations in male infertility diagnosis and prognosis.
Assessment of sperm DNA fragmentation (sDF) has been proposed to discriminate fertile …

COVID-19 and fertility: a virtual reality

G Anifandis, CI Messini, A Daponte… - Reproductive biomedicine …, 2020 - Elsevier
The COVID-19 pandemic is an extraordinary global situation, and all countries have
adopted their own strategies to diminish and eliminate the spread of the virus. All measures …

[HTML][HTML] Oxidation of sperm DNA and male infertility

L Rashki Ghaleno, AR Alizadeh, JR Drevet… - Antioxidants, 2021 - mdpi.com
One important reason for male infertility is oxidative stress and its destructive effects on
sperm structures and functions. The particular composition of the sperm membrane, rich in …

[HTML][HTML] Oxidative stress and reproductive function: The protection of mammalian spermatozoa against oxidative stress

C O'Flaherty, E Scarlata - Reproduction, 2022 - rep.bioscientifica.com
In brief This review focuses on the enzymatic antioxidant mechanisms to fight oxidative
stress by spermatozoa, highlighting the differences among mammalian species. We discuss …

An update on clinical and surgical interventions to reduce sperm DNA fragmentation in infertile men

SC Esteves, D Santi, M Simoni - Andrology, 2020 - Wiley Online Library
Background Sperm chromatin integrity is essential for normal embryo development and
pregnancy outcome. Sperm DNA fragmentation (SDF) testing constitutes a diagnostic tool to …

[HTML][HTML] Oxidative stress in male infertility: causes, effects in assisted reproductive techniques, and protective support of antioxidants

J Ribas-Maynou, M Yeste - Biology, 2020 - mdpi.com
The spermatozoon is a highly specialized cell, whose main function is the transport of the
intact male genetic material into the oocyte. During its formation and transit throughout male …

[HTML][HTML] Reproductive effects of cadmium on sperm function and early embryonic development in vitro

L Zhao, Y Ru, M Liu, J Tang, J Zheng, B Wu, Y Gu… - PloS one, 2017 - journals.plos.org
Cadmium is a major environmental toxicant that is released into the atmosphere, water and
soil in the form of cadmium oxide, cadmium chloride, or cadmium sulfide via industrial …

[HTML][HTML] Osteoarthritis and toll-like receptors: when innate immunity meets chondrocyte apoptosis

G Barreto, M Manninen, K K. Eklund - Biology, 2020 - mdpi.com
Osteoarthritis (OA) has long been viewed as a degenerative disease of cartilage, but
accumulating evidence indicates that inflammation has a critical role in its pathogenesis. In …

[HTML][HTML] The impact of oxidative stress on male reproductive function: Exploring the role of antioxidant supplementation

G Walke, SS Gaurkar, R Prasad, T Lohakare… - Cureus, 2023 - ncbi.nlm.nih.gov
Male reproductive function is highly susceptible to oxidative stress, which arises from an
imbalance between reactive oxygen species (ROS) production and antioxidant defense …

[HTML][HTML] The effects of oral antioxidants on the semen of men with idiopathic oligoasthenoteratozoospermia

AT Alahmar - Clinical and Experimental Reproductive Medicine, 2018 - ncbi.nlm.nih.gov
It has been estimated that approximately 15% of reproductive-age couples suffer from
infertility. Male factors contribute to almost half of infertility cases, and in many patients the …