Overdose mortality rates for opioids and stimulant drugs are substantially higher in men than in women: state-level analysis

ER Butelman, Y Huang, DH Epstein… - …, 2023 - nature.com
Drug overdoses from opioids and stimulants are a major cause of mortality in the United
States. It is unclear if there are stable sex differences in overdose mortality for these drugs …

Does chronic use of amphetamine-type stimulants impair interference control?–A meta-analysis

A Opitz, MS Petasch, R Klappauf, J Kirschgens… - Neuroscience & …, 2023 - Elsevier
In substance use and addiction, inhibitory control is key to ignoring triggers, withstanding
craving and maintaining abstinence. In amphetamine-type stimulant (ATS) users, most …

[HTML][HTML] Past and current drug repurposing clinical trials to treat cognition in methamphetamine use: a scoping review of pharmacotherapy candidates

MMS Peters, CHJ Park, A Turner, AA Guerin… - Addiction …, 2023 - Elsevier
Globally, methamphetamine is one of the most widely used illicit substances. Despite this,
there are no Food and Drug Administration (FDA)-approved pharmacotherapies for treating …

Distinct roles for orexin-1 and orexin-2 receptors in the dentate gyrus of the hippocampus in the methamphetamine-seeking behavior in the rats

F Nazari-Serenjeh, R Azizbeigi, M Rashvand… - Life Sciences, 2023 - Elsevier
Because of the relapsing properties of psychostimulants such as methamphetamine (Meth),
there is no established pharmacotherapy for Meth addiction. The orexinergic system is a …

Methamphetamine exposure drives cell cycle exit and aberrant differentiation in rat hippocampal-derived neurospheres

S Wang, L Wang, Q Bu, Q Wei, L Jiang, Y Dai… - Frontiers in …, 2023 - frontiersin.org
Introduction: Methamphetamine (METH) abuse by pregnant drug addicts causes toxic effects
on fetal neurodevelopment; however, the mechanism underlying such effect of METH is …

Sex‐specific metabolic signatures in methamphetamine addicts

Z Cheng, Y Peng, J Wen, W Chen, W Pan… - Addiction …, 2023 - Wiley Online Library
Methamphetamine (METH) is a commonly abused addictive psychostimulant, and METH‐
induced neurotoxic and behavioural deficits are in a sex‐specific manner. However, there is …

[HTML][HTML] Conditioned inhibition of amphetamine sensitization

AM Guillory, SH Herrera, LK Baker, N Bubula… - Neurobiology of learning …, 2022 - Elsevier
Repeated intermittent exposure to psychostimulants, such as amphetamine, leads to a
progressive enhancement of the drug's ability to increase both behavioral and brain …

The Atypical Dopamine Transporter Inhibitor CE-158 Enhances Dopamine Neurotransmission in the Prefrontal Cortex of Male Rats: A Behavioral, Electrophysiological …

C Sagheddu, E Cancedda, F Bagheri… - International Journal …, 2023 - academic.oup.com
Background Dopamine plays a key role in several physiological functions such as motor
control, learning and memory, and motivation and reward. The atypical dopamine …

Compulsive methamphetamine self-administration in the presence of adverse consequences is associated with increased hippocampal mRNA expression of cellular …

C Munoz, S Jayanthi, B Ladenheim… - Frontiers in Molecular …, 2023 - frontiersin.org
Methamphetamine (METH) is a popular but harmful psychostimulant. METH use disorder
(MUD) is characterized by compulsive and continued use despite adverse life …

[HTML][HTML] Modeling Methamphetamine Use Disorder and Relapse in Animals: Short-and Long-term Epigenetic, Transcriptional., and Biochemical Consequences in the …

K Elhadi, AP Daiwile, JL Cadet - Neuroscience & Biobehavioral Reviews, 2023 - Elsevier
Methamphetamine use disorder (MUD) is a neuropsychiatric disorder characterized by
binge drug taking episodes, intervals of abstinence, and relapses to drug use even during …