Epithelial-to-mesenchymal transition (EMT) determines the most lethal features of cancer,
metastasis formation and chemoresistance, and therefore represents an attractive target in …

The clinical application of immunotherapy is the milestone of cancer treatment. However,
some patients have bad reaction. Cyclooxygenase-2 (COX-2) is frequently expressed in …

Elevated expression of COX‐2 and increased levels of PGE2 are found in numerous
cancers and are associated with tumour development and progression. Although …

Nonsmall cell lung cancer (NSCLC) is a leading cause of global cancer mortality. Recently,
combinatorial treatment approaches have shown promise as they better address tumor …

Simple Summary Inflammation is the biological response of the body to damaging and toxic
stimuli, and is a positive event that evolves with the resolution of critical events (acute …

The purpose of this meta-analysis was to evaluate the efficacy and safety of celecoxib, a
selective cyclooxygenase-2 (COX-2) inhibitor, in addition to standard anticancer therapy …

Background: Digital clubbing and hypertrophic osteoarthropathy (HOA) form a diagnostic
challenge. Subtle presentations of clubbing are often missed. The underlying …

Radiotherapy alone or in combination with chemotherapy/surgery is widely used for
treatment of cancers. It reduces tumor growth and prevents metastasis. While ionizing …

Purpose Preclinical studies demonstrated anti-tumor efficacy of the combination of the
histone deacetylase (HDAC) inhibitor romidepsin plus erlotinib in non-small cell lung cancer …

Background Evidence on the benefits of combining cyclooxygenase-2 inhibitor (COX-2) in
treating non-small cell lung cancer (NSCLC) is still controversial. We investigated the …