Imaging awake animals is quickly gaining traction in neuroscience as it offers a means to
eliminate the confounding effects of anesthesia, difficulties of inter-species translation (when …

Major depressive disorder is a growing and poorly understood pathology. Due to technical
and ethical limitations, a significant proportion of the research on depressive disorders …

The utility of chemical exchange saturation transfer (CEST) MRI for monitoring the uptake of
glucosamine (GlcN), a safe dietary supplement, has been previously demonstrated in …

We investigated the effect of isoflurane and ketamine-xylazine anesthesia on the positron
emission tomography (PET) tracer [18F] SynVesT-1 in the mouse brain.[18F] SynVesT-1 …

The numbers of diagnostic and therapeutic nuclear medicine agents under investigation are
rapidly increasing. Both novel emitters and novel carrier molecules require careful selection …

Today preclinical PET imaging connects laboratory research with clinical applications. Here
PET clearly bridges the gap, as nearly identical imaging protocols can be applied to both …

Objective. In positron emission tomography (PET) rigid motion correction, erroneous tracking
information translates into reduced quality in motion corrected reconstructions. We aim to …

There is always a balance to be struck when designing PET systems; overall performance
depends on spatial resolution, detection sensitivity, and timing performance, all of which are …

We verified if cocaine‐induced peripheral activation might disrupt [18F] FDG brain uptake
after a cocaine challenge and suggested an optimal protocol to measure cocaine‐induced …

Positron emission tomography (PET) imaging studies in laboratory animals are almost
always performed under isoflurane anesthesia to ensure that the subject stays still during …