In the last 20 years, there has been an increased focus on gender differences in health and
disease. The earliest studies of lung cancer enrolled mainly men, as the incidence of lung …

Emerging evidence indicates a novel mode of epidermal growth factor receptor (EGFR)
signaling, notably, one involves EGFR nuclear translocalization and subsequent gene …

Purpose Lung cancer mortality has been shown to vary by race and ethnicity in cancer
registries; however, studies often do not account for smoking status. We sought to …

Abstract Background Cyclooxygenase-2 (COX-2) has recently been considered to promote
lymphangiogenesis by up-regulating vascular endothelial growth factor-C (VEGF-C) in …

Background To evaluate the expression of EGFR and COX-2 and their correlation with
prognosis in NSCLC Methods The paraffin embedded tumor samples of 50 NSCLC patients …

Canine mammary tumours (CMTs) are reported to express cyclo-oxygenase (COX)-2 and
epidermal growth factor receptor (EGFR); however, no studies have evaluated concurrent …

BACKGROUND: We investigated the prognostic value of cyclooxygenase-2 (COX-2) for
survival of patients with non-small cell lung cancer (NSCLC). METHODS: We performed a …

Abstract Cyclooxygenase-2 (COX-2) is an enzyme that has been extensively investigated as
a prognostic marker in cancer. In non-small cell lung cancer (NSCLC) previous results …

Although the relationships between CXCR4 and EGFR expression and survival in non‑small
cell lung cancer (NSCLC) have been studied independently, dual CXCR4/EGFR tumor …

Purpose Adenocarcinoma, the most common non-small cell lung cancer is a leading cause
of death worldwide, with a low overall survival (OS) despite increasing attempts to achieve …