Trace metals are essential micronutrients required for survival across all kingdoms of life.
From bacteria to animals, metals have critical roles as both structural and catalytic cofactors …

Traditional organic antimicrobials mainly act on specific biochemical processes such as
replication, transcription and translation. However, the emergence and wide spread of …

Clinical reports have highlighted the radical increase of antibiotic resistance. As a result,
multidrug resistance has emerged as a serious threat to human health. Many organic …

Meningitis is an inflammation of the meninges and subarachnoid space that can also involve
the brain cortex and parenchyma. It can be acquired spontaneously in the community …

Acinetobacter baumannii is an emerging pathogen that poses a global health threat due to a
lack of therapeutic options for treating drug-resistant strains. In addition to acquiring …

Iron is indispensable for almost all forms of life but toxic at elevated levels,,–. To survive
within their hosts, bacterial pathogens have evolved iron uptake, storage and detoxification …

Highlights•Iron and manganese are withheld from the phagosome to inhibit bacterial
growth.•Excess copper and zinc are used to directly intoxicate intracellular …

Necrotizing enterocolitis (NEC) is among the most relevant gastrointestinal diseases
affecting mostly prematurely born infants with low birth weight. While intestinal dysbiosis has …

Iron is a transition metal utilized by nearly all forms of life for essential cellular processes,
such as DNA synthesis and cellular respiration. During infection by bacterial pathogens, the …

Nutrient transition metals are required cofactors for many proteins to perform functions
necessary for life. As such, the concentration of nutrient metals is carefully maintained to …