The ability of articular cartilage to repair itself is limited because it lacks blood vessels,
nerves, and lymph tissue. Once damaged, it can lead to joint swelling and pain, accelerating …

Macrophages are the most abundant immune cells within the synovial joints, and also the
main innate immune effector cells triggering the initial inflammatory responses in the …

Background Osteoarthritis (OA) is the most common degenerative joint disease primarily
characterized by cartilage destruction. The aim of this study was to investigate the role …

Cannabidiol (CBD), the major non-psychoactive phytocannabinoid of Cannabis sativa L., is
one of the most studied compounds in pharmacotherapeutic approaches to treat oxidative …

Synovial joints are complex structures that enable normal locomotion. Following injury, they
undergo a series of changes, including a prevalent inflammatory response. This increases …

In the cornea, resident immune cells are in close proximity to sensory nerves, consistent with
their important roles in the maintenance of nerves in both homeostasis and inflammation …

Osteoarthritis (OA) is a chronic osteoarthropathy characterized by the progressive
degeneration of articular cartilage and synovial inflammation. Early OA clinical treatments …

Interferons (IFNs) induce an antimicrobial state, protecting tissues from infection. Many
viruses inhibit IFN signaling, but whether bacterial pathogens evade IFN responses remains …

Osteoarthritis (OA) is a low-grade inflammatory disorder of the joints that causes
deterioration of the cartilage, bone remodeling, formation of osteophytes, meniscal damage …

Poly-D, L-lactic acid (PDLLA) filler corrects soft tissue volume loss by increasing collagen
synthesis in the dermis; however, the mechanism is not fully understood. Adipose-derived …