Skeletal muscle has an extraordinary regenerative capacity due to the activity of tissue-
specific muscle stem cells. Consequently, these cells have received the most attention in …

Chronic inflammation impairs skeletal muscle regeneration. Although many cells are
involved in chronic inflammation, macrophages seem to play an important role in impaired …

Background: Low-intensity pulsed ultrasound (LIPUS, a form of mechanical stimulation) can
promote skeletal muscle functional repair, but a lack of mechanistic understanding of its …

Skeletal muscle contusion is among the most common injuries in traumatology and clinics of
sports medicine. The injured muscle is vulnerable to re-injury owing to fibrosis formation …

Although most tissue types are capable of some form of self-repair and regeneration, injuries
that are larger than a critical threshold or those occurring in the setting of certain diseases …

Tissue regeneration after body injury has always been a complex problem to resolve for
mammals. In adult mammals, the repair process after tissue injury is often accompanied by …

Progressive weight loss combined with skeletal muscle atrophy, termed cachexia, is a
common comorbidity associated with cancer that results in adverse consequences for the …

5-Fluorouracil (5FU) remains a first-line chemotherapeutic for several cancers despite its
established adverse side effects. Reduced blood counts with cytotoxic chemotherapies not …

Though macrophages are essential for skeletal muscle regeneration, which is a complex
process, the roles and mechanisms of the macrophages in the process of muscle …

5 fluorouracil (5FU) has been a first-choice chemotherapy drug for several cancer types (eg,
colon, breast, head, and neck); however, its efficacy is diminished by patient acquired …