A 'fourth wave'of high mortality involving methamphetamine and cocaine use has been
gathering force in the USA. Availability and use of illicit fentanyls are still the major drivers of …

Background Stimulant drugs are second only to cannabis as the most widely used class of
illicit drug globally, accounting for 68 million past-year consumers. Dependence on …

Despite considerable progress in pharmacotherapy over the past seven decades, many
mental disorders remain insufficiently treated. This situation is in part due to the limited …

The current opioid epidemic in the United States has been characterized as having three
waves: prescription opioid use, followed by heroin use, and then use of synthetic opioids …

Men who have sex with men (MSM) in the USA were the first population to be identified with
AIDS and continue to be at very high risk of HIV acquisition. We did a systematic literature …

Importance There are no medications approved by authorities for the treatment of
amphetamine or methamphetamine dependence, and studies investigating the …

Numerous studies have identified an association between the use of drugs in sexual
contexts (chemsex) and HIV among gay, bisexual, and other men who have sex with men …

Opioid use disorder (OUD) is increasingly recognized as a chronic, relapsing brain disease
whose treatment should be integrated into primary care settings alongside other chronic …

Background and Objectives Methamphetamine use is increasing in the United States,
potentially including the simultaneous injection of methamphetamine with heroin (goofball) …

Objectives The current guidelines aim to evaluate the role of pharmacological agents in the
treatment of patients with compulsive sexual behaviour disorder (CSBD). They are intended …