Pain is the dominant symptom of osteoarthritis (OA) and available analgesic treatments offer
inadequate pain relief. The capsaicin receptor, TRPV1 is considered to be a promising …

Simple summary Osteoarthritis is affecting several species including the horse. Transient
receptor potential vanilloid 1 (TRPV1)—also known as the 'chili receptor'—is currently being …

Objective: Previous studies have examined the role of sensory nerves and neural mediators
in symmetrical joint inflammation and autoimmunity in rheumatoid arthritis (RA). In this study …

Radiating pain is a significant feature of chronic musculoskeletal pain conditions such as
radiculopathies, repetitive motion disorders and whiplash associated disorders. It is reported …

Serotonin can be released from many different types of immune cells and platelets and is
related to inflammatory responses. Growing evidence has suggested that serotonin is a pro …

L'arthrose (OA) est l'atteinte la plus répandue chez les animaux de compagnie et se
manifeste par l'apparition de douleurs chroniques et d'incapacités fonctionnelles. En …

People suffering from chronic widespread pain, which include those diagnosed with non-
specific arm pain, whiplash associated disorder, fibromyalgia and complex regional pain …

Background. This study was performed to develop therapeutic targets of osteoarthritis (OA)
that can be targeted to alleviate OA development (ie, cartilage destruction) and relieve the …

Executive Summary Over the past 15-20 years, AWI has funded a significant program of vital
research into understanding painful husbandry procedures, developing alternative …

Osteoarthritis is a common disease among joint diseases and all chronic diseases. Knee
osteoarthritis affects a large population of the society and causes disability. Pain is the main …