Herpes simplex viruses

RJ Whitley, DW Kimberlin, B Roizman - Clinical Infectious Diseases, 1998 - JSTOR
Herpes simplex virus (HSV) infections of humans were first documented in ancient Greece.
Greek scholars, particularly Hippocrates, used the word" herpes," meaning to creep or crawl …

[HTML][HTML] Molecular determinants and the regulation of human cytomegalovirus latency and reactivation

D Collins-McMillen, J Buehler, M Peppenelli… - Viruses, 2018 - mdpi.com
Human cytomegalovirus (HCMV) is a beta herpesvirus that establishes a life-long
persistence in the host, like all herpesviruses, by way of a latent infection. During latency …

[HTML][HTML] TLR3 controls constitutive IFN-β antiviral immunity in human fibroblasts and cortical neurons

D Gao, MJ Ciancanelli, P Zhang… - The Journal of …, 2022 - Am Soc Clin Investig
Human herpes simplex virus 1 (HSV-1) encephalitis can be caused by inborn errors of the
TLR3 pathway, resulting in impairment of CNS cell-intrinsic antiviral immunity. Deficiencies …

[HTML][HTML] Antiviral activity of tannic acid modified silver nanoparticles: potential to activate immune response in herpes genitalis

P Orłowski, A Kowalczyk, E Tomaszewska… - Viruses, 2018 - mdpi.com
(1) Background: Tannic acid is a plant-derived polyphenol showing antiviral activity mainly
because of an interference with the viral adsorption. In this work, we tested whether the …

[HTML][HTML] Herpes simplex virus 1 infection of neuronal and non-neuronal cells elicits specific innate immune responses and immune evasion mechanisms

AL Verzosa, LA McGeever, SJ Bhark… - Frontiers in …, 2021 - frontiersin.org
Alphaherpesviruses (α-HV) are a large family of double-stranded DNA viruses which cause
many human and animal diseases. There are three human α-HVs: Herpes Simplex Viruses …

[HTML][HTML] Strength in diversity: Understanding the pathways to herpes simplex virus reactivation

JB Suzich, AR Cliffe - Virology, 2018 - Elsevier
Herpes simplex virus (HSV) establishes a latent infection in peripheral neurons and can
periodically reactivate to cause disease. Reactivation can be triggered by a variety of stimuli …

[HTML][HTML] Evasion of host antiviral innate immunity by HSV-1, an update

C Su, G Zhan, C Zheng - Virology journal, 2016 - Springer
Herpes simplex virus type 1 (HSV-1) infection triggers a rapid induction of host innate
immune responses. The type I interferon (IFN) signal pathway is a central aspect of host …

[HTML][HTML] Herpesviruses: harmonious pathogens but relevant cofactors in other diseases?

S Sehrawat, D Kumar, BT Rouse - Frontiers in cellular and infection …, 2018 - frontiersin.org
Most vertebrates are infected with one or more herpesviruses and remain so for the rest of
their lives. The relationship of immunocompetent healthy host with herpesviruses may …

[HTML][HTML] Covert infection of insects by baculoviruses

T Williams, C Virto, R Murillo, P Caballero - Frontiers in microbiology, 2017 - frontiersin.org
Baculoviruses (Baculoviridae) are occluded DNA viruses that are lethal pathogens of the
larval stages of some lepidopterans, mosquitoes, and sawflies (phytophagous …

Herpesvirus: an underestimated virus

DZ Rechenchoski, LC Faccin-Galhardi… - Folia microbiologica, 2017 - Springer
Herpes simplex virus (HSV) infections are common and widespread; nevertheless, their
outcome can be of unpredictable prognosis in neonates and in immunosuppressed patients …